Irina. Ingold, et.al., Expression of a Catalytically Inactive Mutant Form of Glutathione Peroxidase 4 (Gpx4) Confers a Dominant-negative Effect in Male Fertility., The Journal of biological chemistry, 2015, 290

http://rdf.ncbi.nlm.nih.gov/pubmed/25922076

Irina. Ingold, et.al., Expression of a Catalytically Inactive Mutant Form of Glutathione Peroxidase 4 (Gpx4) Confers a Dominant-negative Effect in Male Fertility., The Journal of biological chemistry, 2015, 290

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gpx4<tm4Marc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5769979

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal sperm mitochondrial sheath morphology_Gpx4<tm4Marc>/Gpx4<+>
  http://metadb.riken.jp/0009832I129S6SvEvTacC57BL6JGpx4tm4MarcGpx4Gpx4tm4MarcGpx4
• decreased litter size_Gpx4<tm4Marc>/Gpx4<+>
  http://metadb.riken.jp/0001935I129S6SvEvTacC57BL6JGpx4tm4MarcGpx4Gpx4tm4MarcGpx4
• abnormal sperm head morphology_Gpx4<tm4Marc>/Gpx4<+>
  http://metadb.riken.jp/0009230I129S6SvEvTacC57BL6JGpx4tm4MarcGpx4Gpx4tm4MarcGpx4
• abnormal sperm physiology_Gpx4<tm4Marc>/Gpx4<+>
  http://metadb.riken.jp/0004543I129S6SvEvTacC57BL6JGpx4tm4MarcGpx4Gpx4tm4MarcGpx4
• kinked sperm flagellum_Gpx4<tm4Marc>/Gpx4<+>
  http://metadb.riken.jp/0009237I129S6SvEvTacC57BL6JGpx4tm4MarcGpx4Gpx4tm4MarcGpx4
• abnormal sperm midpiece morphology_Gpx4<tm4Marc>/Gpx4<+>
  http://metadb.riken.jp/0009831I129S6SvEvTacC57BL6JGpx4tm4MarcGpx4Gpx4tm4MarcGpx4
• failure to gastrulate_Gpx4<tm4Marc>/Gpx4<tm4Marc>
  http://metadb.riken.jp/0001696I129S6SvEvTacC57BL6JGpx4tm4MarcGpx4tm4MarcGpx4tm4Marc
• impaired fertilization_Gpx4<tm4Marc>/Gpx4<+>
  http://metadb.riken.jp/0000242I129S6SvEvTacC57BL6JGpx4tm4MarcGpx4Gpx4tm4MarcGpx4
• abnormal germ layer development_Gpx4<tm4Marc>/Gpx4<tm4Marc>
  http://metadb.riken.jp/0001674I129S6SvEvTacC57BL6JGpx4tm4MarcGpx4tm4MarcGpx4tm4Marc
• embryonic lethality between implantation and placentation, complete penetrance_Gpx4<tm4Marc>/Gpx4<tm4Marc>
  http://metadb.riken.jp/0011095I129S6SvEvTacC57BL6JGpx4tm4MarcGpx4tm4MarcGpx4tm4Marc
• decreased fertilization frequency_Gpx4<tm4Marc>/Gpx4<+>
  http://metadb.riken.jp/0009647I129S6SvEvTacC57BL6JGpx4tm4MarcGpx4Gpx4tm4MarcGpx4
• reduced male fertility_Gpx4<tm4Marc>/Gpx4<+>
  http://metadb.riken.jp/0001922I129S6SvEvTacC57BL6JGpx4tm4MarcGpx4Gpx4tm4MarcGpx4
• empty decidua capsularis_Gpx4<tm4Marc>/Gpx4<tm4Marc>
  http://metadb.riken.jp/0009687I129S6SvEvTacC57BL6JGpx4tm4MarcGpx4tm4MarcGpx4tm4Marc
• abnormal sperm motility_Gpx4<tm4Marc>/Gpx4<+>
  http://metadb.riken.jp/0002674I129S6SvEvTacC57BL6JGpx4tm4MarcGpx4Gpx4tm4MarcGpx4
• abnormal embryonic tissue morphology_Gpx4<tm4Marc>/Gpx4<tm4Marc>
  http://metadb.riken.jp/0002085I129S6SvEvTacC57BL6JGpx4tm4MarcGpx4tm4MarcGpx4tm4Marc
• abnormal extraembryonic tissue morphology_Gpx4<tm4Marc>/Gpx4<tm4Marc>
  http://metadb.riken.jp/0002086I129S6SvEvTacC57BL6JGpx4tm4MarcGpx4tm4MarcGpx4tm4Marc

class

http://purl.org/net/cito/citesAsAuthority

• Gpx4<tm4Marc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5769979