embryonic lethality during organogenesis, complete penetrance_Srf<tm1Rjs>/Srf<tm2.1Nor>,Tg(Myh6-cre)2182Mds/0

http://metadb.riken.jp/0011098I129P2OlaHsd129S7SvEvBrdC57BL6FVBNSrftm1RjsSrftm21NorTgMyh6cre2182Mds0Srftm21NorTgMyh6cre2182MdsSrftm1Rjs

embryonic lethality during organogenesis, complete penetrance_Srf<tm1Rjs>/Srf<tm2.1Nor>,Tg(Myh6-cre)2182Mds/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2182, Michael D Schneider
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447636
• serum response factor
  http://metadb.riken.jp/db/mgi_rdf/MGI:106658

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Srf<tm1Rjs>/Srf<tm2.1Nor>,Tg(Myh6-cre)2182Mds/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Srf<tm2.1Nor>|Tg(Myh6-cre)2182Mds|Srf<tm1Rjs>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011098

文献

http://purl.org/net/cito/citesAsAuthority

• Zhiyv. Niu, et.al., Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets., The Journal of biological chemistry, 2005, 280
  http://rdf.ncbi.nlm.nih.gov/pubmed/15929941