Zhiyv. Niu, et.al., Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets., The Journal of biological chemistry, 2005, 280

http://rdf.ncbi.nlm.nih.gov/pubmed/15929941

Zhiyv. Niu, et.al., Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets., The Journal of biological chemistry, 2005, 280

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• embryonic lethality, complete penetrance_Srf<tm1Rjs>/Srf<tm1Rjs>
  http://metadb.riken.jp/0011092I129S7SvEvBrdC57BL6Srftm1RjsSrftm1RjsSrftm1Rjs
• pericardial effusion_Srf<tm1Rjs>/Srf<tm2.1Nor>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0005312I129P2OlaHsd129S7SvEvBrdC57BL6FVBNSrftm1RjsSrftm21NorTgMyh6cre2182Mds0Srftm21NorTgMyh6cre2182MdsSrftm1Rjs
• abnormal fetal atrioventricular canal morphology_Srf<tm1Rjs>/Srf<tm2.1Nor>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0006107I129P2OlaHsd129S7SvEvBrdC57BL6FVBNSrftm1RjsSrftm21NorTgMyh6cre2182Mds0Srftm21NorTgMyh6cre2182MdsSrftm1Rjs
• abnormal myocardium layer morphology_Srf<tm1Rjs>/Srf<tm2.1Nor>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0005329I129P2OlaHsd129S7SvEvBrdC57BL6FVBNSrftm1RjsSrftm21NorTgMyh6cre2182Mds0Srftm21NorTgMyh6cre2182MdsSrftm1Rjs
• abnormal interventricular groove morphology_Srf<tm1Rjs>/Srf<tm2.1Nor>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0004032I129P2OlaHsd129S7SvEvBrdC57BL6FVBNSrftm1RjsSrftm21NorTgMyh6cre2182Mds0Srftm21NorTgMyh6cre2182MdsSrftm1Rjs
• irregular heartbeat_Srf<tm1Rjs>/Srf<tm2.1Nor>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0001636I129P2OlaHsd129S7SvEvBrdC57BL6FVBNSrftm1RjsSrftm21NorTgMyh6cre2182Mds0Srftm21NorTgMyh6cre2182MdsSrftm1Rjs
• embryonic lethality during organogenesis, complete penetrance_Srf<tm1Rjs>/Srf<tm2.1Nor>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0011098I129P2OlaHsd129S7SvEvBrdC57BL6FVBNSrftm1RjsSrftm21NorTgMyh6cre2182Mds0Srftm21NorTgMyh6cre2182MdsSrftm1Rjs
• abnormal heart ventricle morphology_Srf<tm1Rjs>/Srf<tm2.1Nor>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0005294I129P2OlaHsd129S7SvEvBrdC57BL6FVBNSrftm1RjsSrftm21NorTgMyh6cre2182Mds0Srftm21NorTgMyh6cre2182MdsSrftm1Rjs
• increased cardiomyocyte apoptosis_Srf<tm1Rjs>/Srf<tm2.1Nor>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0003222I129P2OlaHsd129S7SvEvBrdC57BL6FVBNSrftm1RjsSrftm21NorTgMyh6cre2182Mds0Srftm21NorTgMyh6cre2182MdsSrftm1Rjs
• abnormal pericardium morphology_Srf<tm1Rjs>/Srf<tm2.1Nor>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0000288I129P2OlaHsd129S7SvEvBrdC57BL6FVBNSrftm1RjsSrftm21NorTgMyh6cre2182Mds0Srftm21NorTgMyh6cre2182MdsSrftm1Rjs
• distended pericardium_Srf<tm1Rjs>/Srf<tm2.1Nor>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0000292I129P2OlaHsd129S7SvEvBrdC57BL6FVBNSrftm1RjsSrftm21NorTgMyh6cre2182Mds0Srftm21NorTgMyh6cre2182MdsSrftm1Rjs
• abnormal interventricular septum morphology_Srf<tm1Rjs>/Srf<tm2.1Nor>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0000281I129P2OlaHsd129S7SvEvBrdC57BL6FVBNSrftm1RjsSrftm21NorTgMyh6cre2182Mds0Srftm21NorTgMyh6cre2182MdsSrftm1Rjs
• abnormal gastrulation_Srf<tm1Rjs>/Srf<tm1Rjs>
  http://metadb.riken.jp/0001695I129S7SvEvBrdC57BL6Srftm1RjsSrftm1RjsSrftm1Rjs
• embryonic growth arrest_Srf<tm1Rjs>/Srf<tm2.1Nor>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0001730I129P2OlaHsd129S7SvEvBrdC57BL6FVBNSrftm1RjsSrftm21NorTgMyh6cre2182Mds0Srftm21NorTgMyh6cre2182MdsSrftm1Rjs