embryonic lethality during organogenesis, complete penetrance_Bub1<Gt(XG453)Byg>/Bub1<tm1.1Tvd>

http://metadb.riken.jp/0011098I129P2OlaHsdC57BL6JBub1GtXG453BygBub1tm11TvdBub1GtXG453BygBub1tm11Tvd

embryonic lethality during organogenesis, complete penetrance_Bub1<Gt(XG453)Byg>/Bub1<tm1.1Tvd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• BUB1, mitotic checkpoint serine/threonine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:1100510

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bub1<Gt(XG453)Byg>/Bub1<tm1.1Tvd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Bub1<Gt(XG453)Byg>|Bub1<tm1.1Tvd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011098

文献

http://purl.org/net/cito/citesAsAuthority

• Mark. Schliekelman, et.al., Impaired Bub1 function in vivo compromises tension-dependent checkpoint function leading to aneuploidy and tumorigenesis., Cancer research, 2009, 69
  http://rdf.ncbi.nlm.nih.gov/pubmed/19117986