embryonic lethality during organogenesis, complete penetrance_Gt(ROSA)26Sor<tm1(Notch1)Dam>/Gt(ROSA)26Sor<+>,Tg(Neurog3-cre/Esr1*)1Dam/0

http://metadb.riken.jp/0011098I129S4SvJaeC57BL6CBAGtROSA26Sortm1Notch1DamGtROSA26SorTgNeurog3creEsr11Dam0GtROSA26Sortm1Notch1DamTgNeurog3creEsr11DamGtROSA26Sor

embryonic lethality during organogenesis, complete penetrance_Gt(ROSA)26Sor<tm1(Notch1)Dam>/Gt(ROSA)26Sor<+>,Tg(Neurog3-cre/Esr1*)1Dam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Douglas A Melton
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684325
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(Notch1)Dam>/Gt(ROSA)26Sor<+>,Tg(Neurog3-cre/Esr1*)1Dam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm1(Notch1)Dam>|Tg(Neurog3-cre/Esr1*)1Dam|Gt(ROSA)26Sor<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011098

文献

http://purl.org/net/cito/citesAsAuthority

• L Charles. Murtaugh, et.al., Notch signaling controls multiple steps of pancreatic differentiation., Proceedings of the National Academy of Sciences of the United States of America, 2003, 100
  http://rdf.ncbi.nlm.nih.gov/pubmed/14657333