L Charles. Murtaugh, et.al., Notch signaling controls multiple steps of pancreatic differentiation., Proceedings of the National Academy of Sciences of the United States of America, 2003, 100

http://rdf.ncbi.nlm.nih.gov/pubmed/14657333

L Charles. Murtaugh, et.al., Notch signaling controls multiple steps of pancreatic differentiation., Proceedings of the National Academy of Sciences of the United States of America, 2003, 100

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(Notch1)Dam>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684314

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal pancreas development_Gt(ROSA)26Sor<tm1(Notch1)Dam>/Gt(ROSA)26Sor<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0003934I129S4SvJaeC57BL6ICRGtROSA26Sortm1Notch1DamGtROSA26SorTgPdx1cre891Dam0GtROSA26Sortm1Notch1DamGtROSA26SorTgPdx1cre891Dam
• abnormal endocrine pancreas morphology_Gt(ROSA)26Sor<tm1(Notch1)Dam>/Gt(ROSA)26Sor<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009165I129S4SvJaeC57BL6ICRGtROSA26Sortm1Notch1DamGtROSA26SorTgPdx1cre891Dam0GtROSA26Sortm1Notch1DamGtROSA26SorTgPdx1cre891Dam
• no abnormal phenotype detected_Gt(ROSA)26Sor<tm1(Notch1)Dam>/Gt(ROSA)26Sor<tm1(Notch1)Dam>
  http://metadb.riken.jp/0002169I129S4SvJaeC57BL6GtROSA26Sortm1Notch1DamGtROSA26Sortm1Notch1DamGtROSA26Sortm1Notch1Dam
• abnormal pancreas development_Gt(ROSA)26Sor<tm1(Notch1)Dam>/Gt(ROSA)26Sor<+>,Tg(Pdx1-cre/Esr1*)35.10Dam/0
  http://metadb.riken.jp/0003934I129S4SvJaeC57BL6CBAGtROSA26Sortm1Notch1DamGtROSA26SorTgPdx1creEsr13510Dam0GtROSA26SorTgPdx1creEsr13510DamGtROSA26Sortm1Notch1Dam
• decreased pancreatic beta cell number_Gt(ROSA)26Sor<tm1(Notch1)Dam>/Gt(ROSA)26Sor<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0003339I129S4SvJaeC57BL6ICRGtROSA26Sortm1Notch1DamGtROSA26SorTgPdx1cre891Dam0GtROSA26Sortm1Notch1DamGtROSA26SorTgPdx1cre891Dam
• embryonic lethality during organogenesis, complete penetrance_Gt(ROSA)26Sor<tm1(Notch1)Dam>/Gt(ROSA)26Sor<+>,Tg(Neurog3-cre/Esr1*)1Dam/0
  http://metadb.riken.jp/0011098I129S4SvJaeC57BL6CBAGtROSA26Sortm1Notch1DamGtROSA26SorTgNeurog3creEsr11Dam0GtROSA26Sortm1Notch1DamTgNeurog3creEsr11DamGtROSA26Sor
• abnormal exocrine pancreas morphology_Gt(ROSA)26Sor<tm1(Notch1)Dam>/Gt(ROSA)26Sor<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0005220I129S4SvJaeC57BL6ICRGtROSA26Sortm1Notch1DamGtROSA26SorTgPdx1cre891Dam0GtROSA26Sortm1Notch1DamGtROSA26SorTgPdx1cre891Dam
• decreased pancreatic alpha cell number_Gt(ROSA)26Sor<tm1(Notch1)Dam>/Gt(ROSA)26Sor<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009177I129S4SvJaeC57BL6ICRGtROSA26Sortm1Notch1DamGtROSA26SorTgPdx1cre891Dam0GtROSA26Sortm1Notch1DamGtROSA26SorTgPdx1cre891Dam
• absent pancreatic alpha cells_Gt(ROSA)26Sor<tm1(Notch1)Dam>/Gt(ROSA)26Sor<+>,Tg(Neurog3-cre/Esr1*)1Dam/0
  http://metadb.riken.jp/0009178I129S4SvJaeC57BL6CBAGtROSA26Sortm1Notch1DamGtROSA26SorTgNeurog3creEsr11Dam0GtROSA26Sortm1Notch1DamTgNeurog3creEsr11DamGtROSA26Sor

class

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(Notch1)Dam>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684314