embryonic lethality during organogenesis, complete penetrance_Mlst8<tm1Lex>/Mlst8<tm1Lex>

http://metadb.riken.jp/0011098I129S5SvEvBrdMlst8tm1LexMlst8tm1LexMlst8tm1Lex

embryonic lethality during organogenesis, complete penetrance_Mlst8<tm1Lex>/Mlst8<tm1Lex>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• MTOR associated protein, LST8 homolog (S. cerevisiae)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1929514

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mlst8<tm1Lex>/Mlst8<tm1Lex>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mlst8<tm1Lex>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S5/SvEvBrd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011098

文献

http://purl.org/net/cito/citesAsAuthority

• David A. Guertin, et.al., Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1., Developmental cell, 2006, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/17141160