David A. Guertin, et.al., Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1., Developmental cell, 2006, 11

http://rdf.ncbi.nlm.nih.gov/pubmed/17141160

David A. Guertin, et.al., Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1., Developmental cell, 2006, 11

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mlst8<tm1Lex>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3528742
• Mtor<Gt(OST92090)Lex>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3529989

class

http://purl.org/net/cito/citesAsAuthority

• Mlst8<tm1Lex>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3528742
• Mtor<Gt(OST92090)Lex>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3529989

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal heart development_Mlst8<tm1Lex>/Mlst8<tm1Lex>
  http://metadb.riken.jp/0000267I129S5SvEvBrdMlst8tm1LexMlst8tm1LexMlst8tm1Lex
• abnormal brain development_Mlst8<tm1Lex>/Mlst8<tm1Lex>
  http://metadb.riken.jp/0000913I129S5SvEvBrdMlst8tm1LexMlst8tm1LexMlst8tm1Lex
• abnormal telencephalon development_Mlst8<tm1Lex>/Mlst8<tm1Lex>
  http://metadb.riken.jp/0000934I129S5SvEvBrdMlst8tm1LexMlst8tm1LexMlst8tm1Lex
• internal hemorrhage_Mlst8<tm1Lex>/Mlst8<tm1Lex>
  http://metadb.riken.jp/0001634I129S5SvEvBrdMlst8tm1LexMlst8tm1LexMlst8tm1Lex
• decreased embryo size_Mlst8<tm1Lex>/Mlst8<tm1Lex>
  http://metadb.riken.jp/0001698I129S5SvEvBrdMlst8tm1LexMlst8tm1LexMlst8tm1Lex
• abnormal placenta morphology_Rictor<Gt(RRR347)Byg>/Rictor<Gt(RRR347)Byg>
  http://metadb.riken.jp/0001711I129P2OlaHsdRictorGtRRR347BygRictorGtRRR347BygRictorGtRRR347Byg
他14件を見る
• abnormal placenta morphology_Mlst8<tm1Lex>/Mlst8<tm1Lex>
  http://metadb.riken.jp/0001711I129S5SvEvBrdMlst8tm1LexMlst8tm1LexMlst8tm1Lex
• abnormal vitelline vasculature morphology_Mlst8<tm1Lex>/Mlst8<tm1Lex>
  http://metadb.riken.jp/0003229I129S5SvEvBrdMlst8tm1LexMlst8tm1LexMlst8tm1Lex
• embryonic growth retardation_Rictor<Gt(RRR347)Byg>/Rictor<Gt(RRR347)Byg>
  http://metadb.riken.jp/0003984I129P2OlaHsdRictorGtRRR347BygRictorGtRRR347BygRictorGtRRR347Byg
• embryonic growth retardation_Mlst8<tm1Lex>/Mlst8<tm1Lex>
  http://metadb.riken.jp/0003984I129S5SvEvBrdMlst8tm1LexMlst8tm1LexMlst8tm1Lex
• dilated vasculature_Mlst8<tm1Lex>/Mlst8<tm1Lex>
  http://metadb.riken.jp/0004938I129S5SvEvBrdMlst8tm1LexMlst8tm1LexMlst8tm1Lex
• abnormal trophoblast giant cell morphology_Mtor<Gt(OST92090)Lex>/Mtor<Gt(OST92090)Lex>
  http://metadb.riken.jp/0005033I129S5SvEvBrdMtorGtOST92090LexMtorGtOST92090LexMtorGtOST92090Lex
• abnormal trophoblast giant cell morphology_Rptor<tm1Lex>/Rptor<tm1Lex>
  http://metadb.riken.jp/0005033I129SSvEvBrdRptortm1LexRptortm1LexRptortm1Lex
• embryonic lethality between implantation and somite formation, complete penetrance_Rptor<tm1Lex>/Rptor<tm1Lex>
  http://metadb.riken.jp/0011096I129SSvEvBrdRptortm1LexRptortm1LexRptortm1Lex
• embryonic lethality during organogenesis, complete penetrance_Rictor<Gt(RRR347)Byg>/Rictor<Gt(RRR347)Byg>
  http://metadb.riken.jp/0011098I129P2OlaHsdRictorGtRRR347BygRictorGtRRR347BygRictorGtRRR347Byg
• embryonic lethality during organogenesis, complete penetrance_Mlst8<tm1Lex>/Mlst8<tm1Lex>
  http://metadb.riken.jp/0011098I129S5SvEvBrdMlst8tm1LexMlst8tm1LexMlst8tm1Lex
• thick placenta labyrinth_Rictor<Gt(RRR347)Byg>/Rictor<Gt(RRR347)Byg>
  http://metadb.riken.jp/0011524I129P2OlaHsdRictorGtRRR347BygRictorGtRRR347BygRictorGtRRR347Byg
• thick placenta labyrinth_Mlst8<tm1Lex>/Mlst8<tm1Lex>
  http://metadb.riken.jp/0011524I129S5SvEvBrdMlst8tm1LexMlst8tm1LexMlst8tm1Lex
• decreased inner cell mass proliferation_Rptor<tm1Lex>/Rptor<tm1Lex>
  http://metadb.riken.jp/0012113I129SSvEvBrdRptortm1LexRptortm1LexRptortm1Lex
• absent inner cell mass proliferation_Mtor<Gt(OST92090)Lex>/Mtor<Gt(OST92090)Lex>
  http://metadb.riken.jp/0012114I129S5SvEvBrdMtorGtOST92090LexMtorGtOST92090LexMtorGtOST92090Lex

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD15194
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD15194