embryonic lethality during organogenesis, complete penetrance_Notch1<tm2Rko>/Notch1<tm4(cre)Rko>

http://metadb.riken.jp/0011098I129X1SvJC57BL6Notch1tm2RkoNotch1tm4creRkoNotch1tm4creRkoNotch1tm2Rko

embryonic lethality during organogenesis, complete penetrance_Notch1<tm2Rko>/Notch1<tm4(cre)Rko>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• notch 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97363

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Notch1<tm2Rko>/Notch1<tm4(cre)Rko>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Notch1<tm4(cre)Rko>|Notch1<tm2Rko>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011098

文献

http://purl.org/net/cito/citesAsAuthority

• Zhenyi. Liu, et.al., Notch1 loss of heterozygosity causes vascular tumors and lethal hemorrhage in mice., The Journal of clinical investigation, 2011, 121
  http://rdf.ncbi.nlm.nih.gov/pubmed/21266774