Zhenyi. Liu, et.al., Notch1 loss of heterozygosity causes vascular tumors and lethal hemorrhage in mice., The Journal of clinical investigation, 2011, 121

http://rdf.ncbi.nlm.nih.gov/pubmed/21266774

Zhenyi. Liu, et.al., Notch1 loss of heterozygosity causes vascular tumors and lethal hemorrhage in mice., The Journal of clinical investigation, 2011, 121

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(CBR,hMGFP)Dpiw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5009465
• Notch1<tm4(cre)Rko>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5009236

class

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(CBR,hMGFP)Dpiw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5009465
• Notch1<tm4(cre)Rko>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5009236

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal liver parenchyma morphology_Notch1<tm2Rko>/Notch1<tm3(cre)Rko>
  http://metadb.riken.jp/0008986I129X1SvJC57BL6Notch1tm2RkoNotch1tm3creRkoNotch1tm3creRkoNotch1tm2Rko
• embryonic lethality during organogenesis, complete penetrance_Notch1<tm2Rko>/Notch1<tm4(cre)Rko>
  http://metadb.riken.jp/0011098I129X1SvJC57BL6Notch1tm2RkoNotch1tm4creRkoNotch1tm4creRkoNotch1tm2Rko
• increased hemangioma incidence_Notch1<tm2Rko>/Notch1<tm3(cre)Rko>
  http://metadb.riken.jp/0002947I129X1SvJC57BL6Notch1tm2RkoNotch1tm3creRkoNotch1tm3creRkoNotch1tm2Rko
• hemoperitoneum_Notch1<tm2Rko>/Notch1<tm3(cre)Rko>
  http://metadb.riken.jp/0005435I129X1SvJC57BL6Notch1tm2RkoNotch1tm3creRkoNotch1tm3creRkoNotch1tm2Rko
• extramedullary hematopoiesis_Notch1<tm2Rko>/Notch1<tm3(cre)Rko>
  http://metadb.riken.jp/0000240I129X1SvJC57BL6Notch1tm2RkoNotch1tm3creRkoNotch1tm3creRkoNotch1tm2Rko
• pale liver_Notch1<tm2Rko>/Notch1<tm3(cre)Rko>
  http://metadb.riken.jp/0000603I129X1SvJC57BL6Notch1tm2RkoNotch1tm3creRkoNotch1tm3creRkoNotch1tm2Rko
• enlarged liver sinusoidal spaces_Notch1<tm2Rko>/Notch1<tm3(cre)Rko>
  http://metadb.riken.jp/0000602I129X1SvJC57BL6Notch1tm2RkoNotch1tm3creRkoNotch1tm3creRkoNotch1tm2Rko
• abnormal spleen morphology_Notch1<tm2Rko>/Notch1<tm3(cre)Rko>
  http://metadb.riken.jp/0000689I129X1SvJC57BL6Notch1tm2RkoNotch1tm3creRkoNotch1tm3creRkoNotch1tm2Rko
• abnormal cornea morphology_Notch1<tm2Rko>/Notch1<tm3(cre)Rko>
  http://metadb.riken.jp/0001312I129X1SvJC57BL6Notch1tm2RkoNotch1tm3creRkoNotch1tm3creRkoNotch1tm2Rko
• increased angiogenesis_Notch1<tm2Rko>/Notch1<tm3(cre)Rko>
  http://metadb.riken.jp/0005601I129X1SvJC57BL6Notch1tm2RkoNotch1tm3creRkoNotch1tm3creRkoNotch1tm2Rko
• corneal vascularization_Notch1<tm2Rko>/Notch1<tm3(cre)Rko>
  http://metadb.riken.jp/0005542I129X1SvJC57BL6Notch1tm2RkoNotch1tm3creRkoNotch1tm3creRkoNotch1tm2Rko
• liver inflammation_Notch1<tm2Rko>/Notch1<tm3(cre)Rko>
  http://metadb.riken.jp/0001860I129X1SvJC57BL6Notch1tm2RkoNotch1tm3creRkoNotch1tm3creRkoNotch1tm2Rko
• abnormal hepatic cord morphology_Notch1<tm2Rko>/Notch1<tm3(cre)Rko>
  http://metadb.riken.jp/0012246I129X1SvJC57BL6Notch1tm2RkoNotch1tm3creRkoNotch1tm3creRkoNotch1tm2Rko
• abnormal liver morphology_Notch1<tm2Rko>/Notch1<tm3(cre)Rko>
  http://metadb.riken.jp/0000598I129X1SvJC57BL6Notch1tm2RkoNotch1tm3creRkoNotch1tm3creRkoNotch1tm2Rko
• abnormal vitelline vasculature morphology_Notch1<tm2Rko>/Notch1<tm4(cre)Rko>
  http://metadb.riken.jp/0003229I129X1SvJC57BL6Notch1tm2RkoNotch1tm4creRkoNotch1tm4creRkoNotch1tm2Rko
• corneal deposits_Notch1<tm2Rko>/Notch1<tm3(cre)Rko>
  http://metadb.riken.jp/0005544I129X1SvJC57BL6Notch1tm2RkoNotch1tm3creRkoNotch1tm3creRkoNotch1tm2Rko
• enlarged spleen_Notch1<tm2Rko>/Notch1<tm3(cre)Rko>
  http://metadb.riken.jp/0000691I129X1SvJC57BL6Notch1tm2RkoNotch1tm3creRkoNotch1tm3creRkoNotch1tm2Rko
• abnormal liver lobule morphology_Notch1<tm2Rko>/Notch1<tm3(cre)Rko>
  http://metadb.riken.jp/0008987I129X1SvJC57BL6Notch1tm2RkoNotch1tm3creRkoNotch1tm3creRkoNotch1tm2Rko
• premature death_Notch1<tm2Rko>/Notch1<tm3(cre)Rko>
  http://metadb.riken.jp/0002083I129X1SvJC57BL6Notch1tm2RkoNotch1tm3creRkoNotch1tm3creRkoNotch1tm2Rko