lethality throughout fetal growth and development, complete penetrance_Brca1<tm1Bhk>/Brca1<tm1Bhk>,Cdkn2c<tm1Yxi>/Cdkn2c<tm1Yxi>

http://metadb.riken.jp/0011099C129Cdkn2ctm1YxiBrca1tm1BhkBrca1tm1BhkBrca1tm1BhkCdkn2ctm1YxiCdkn2ctm1YxiCdkn2ctm1YxiBrca1tm1Bhk

lethality throughout fetal growth and development, complete penetrance_Brca1<tm1Bhk>/Brca1<tm1Bhk>,Cdkn2c<tm1Yxi>/Cdkn2c<tm1Yxi>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
  http://metadb.riken.jp/db/mgi_rdf/MGI:105388
• breast cancer 1, early onset
  http://metadb.riken.jp/db/mgi_rdf/MGI:104537

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Brca1<tm1Bhk>/Brca1<tm1Bhk>,Cdkn2c<tm1Yxi>/Cdkn2c<tm1Yxi>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn2c<tm1Yxi>|Brca1<tm1Bhk>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• C.129-Cdkn2c<tm1Yxi> Brca1<tm1Bhk>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete lethality throughout fetal growth and development
  http://purl.obolibrary.org/obo/MP_0011099

文献

http://purl.org/net/cito/citesAsAuthority

• F. Bai, et.al., Germline mutation of Brca1 alters the fate of mammary luminal cells and causes luminal-to-basal mammary tumor transformation., Oncogene, 2013, 32
  http://rdf.ncbi.nlm.nih.gov/pubmed/22777348