lethality throughout fetal growth and development, complete penetrance_Acvrl1<tm2Spo>/Acvrl1<tm2Spo>,Tg(Acvrl1-cre)L1Spo/0

http://metadb.riken.jp/0011099I129129S4SvJaeC57BL6FVBNAcvrl1tm2SpoAcvrl1tm2SpoTgAcvrl1creL1Spo0TgAcvrl1creL1SpoAcvrl1tm2Spo

lethality throughout fetal growth and development, complete penetrance_Acvrl1<tm2Spo>/Acvrl1<tm2Spo>,Tg(Acvrl1-cre)L1Spo/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• activin A receptor, type II-like 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1338946
• transgene insertion L1, S Paul Oh
  http://metadb.riken.jp/db/mgi_rdf/MGI:4398907

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Acvrl1<tm2Spo>/Acvrl1<tm2Spo>,Tg(Acvrl1-cre)L1Spo/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Acvrl1-cre)L1Spo|Acvrl1<tm2Spo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129S4/SvJae * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete lethality throughout fetal growth and development
  http://purl.obolibrary.org/obo/MP_0011099

文献

http://purl.org/net/cito/citesAsAuthority

• Sung O. Park, et.al., ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2., Blood, 2008, 111
  http://rdf.ncbi.nlm.nih.gov/pubmed/17911384