lethality throughout fetal growth and development, complete penetrance_Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>,Palb2<tm1.2Dli>/Palb2<tm1.2Dli>

http://metadb.riken.jp/0011099I129S2SvPas129S4SvJaeSorBALBcJC57BL6Cdkn1atm1TyjCdkn1atm1TyjPalb2tm12DliPalb2tm12DliPalb2tm12DliCdkn1atm1Tyj

lethality throughout fetal growth and development, complete penetrance_Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>,Palb2<tm1.2Dli>/Palb2<tm1.2Dli>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 1A (P21)
  http://metadb.riken.jp/db/mgi_rdf/MGI:104556
• partner and localizer of BRCA2
  http://metadb.riken.jp/db/mgi_rdf/MGI:3040695

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>,Palb2<tm1.2Dli>/Palb2<tm1.2Dli>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Palb2<tm1.2Dli>|Cdkn1a<tm1Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S4/SvJaeSor * BALB/cJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete lethality throughout fetal growth and development
  http://purl.obolibrary.org/obo/MP_0011099

文献

http://purl.org/net/cito/citesAsAuthority

• Christian. Bowman-Colin, et.al., Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110
  http://rdf.ncbi.nlm.nih.gov/pubmed/23657012