lethality throughout fetal growth and development, complete penetrance_Spi1<tm1Sing>/Spi1<tm1Sing>,Spib<tm1Mcs>/Spib<tm1Mcs>

http://metadb.riken.jp/0011099I129SSvEv129X1SvJSpi1tm1SingSpi1tm1SingSpibtm1McsSpibtm1McsSpi1tm1SingSpibtm1Mcs

lethality throughout fetal growth and development, complete penetrance_Spi1<tm1Sing>/Spi1<tm1Sing>,Spib<tm1Mcs>/Spib<tm1Mcs>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Spi-B transcription factor (Spi-1/PU.1 related)
  http://metadb.riken.jp/db/mgi_rdf/MGI:892986
• spleen focus forming virus (SFFV) proviral integration oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:98282

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Spi1<tm1Sing>/Spi1<tm1Sing>,Spib<tm1Mcs>/Spib<tm1Mcs>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Spi1<tm1Sing>|Spib<tm1Mcs>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete lethality throughout fetal growth and development
  http://purl.obolibrary.org/obo/MP_0011099

文献

http://purl.org/net/cito/citesAsAuthority

• L A. Garrett-Sinha, et.al., PU.1 and Spi-B are required for normal B cell receptor-mediated signal transduction., Immunity, 1999, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/10229183