lethality throughout fetal growth and development, complete penetrance_Chuk<tm1Ver>/Chuk<tm1Ver>,Ikbkb<tm1Ver>/Ikbkb<tm1Ver>,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>

http://metadb.riken.jp/0011099I129Sv129S4SvJaeC57BL6JChuktm1VerChuktm1VerIkbkbtm1VerIkbkbtm1VerTnfrsf1atm1MakTnfrsf1atm1MakIkbkbtm1VerTnfrsf1atm1MakChuktm1Ver

lethality throughout fetal growth and development, complete penetrance_Chuk<tm1Ver>/Chuk<tm1Ver>,Ikbkb<tm1Ver>/Ikbkb<tm1Ver>,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• inhibitor of kappaB kinase beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:1338071
• conserved helix-loop-helix ubiquitous kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:99484
• tumor necrosis factor receptor superfamily, member 1a
  http://metadb.riken.jp/db/mgi_rdf/MGI:1314884

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Chuk<tm1Ver>/Chuk<tm1Ver>,Ikbkb<tm1Ver>/Ikbkb<tm1Ver>,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ikbkb<tm1Ver>|Tnfrsf1a<tm1Mak>|Chuk<tm1Ver>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129S4/SvJae * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete lethality throughout fetal growth and development
  http://purl.obolibrary.org/obo/MP_0011099

文献

http://purl.org/net/cito/citesAsAuthority

• Q. Li, et.al., Complete lack of NF-kappaB activity in IKK1 and IKK2 double-deficient mice: additional defect in neurulation., Genes & development, 2000, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/10898787