preweaning lethality, complete penetrance_Mdm4<Gt(VICTR20)7Lex>/Mdm4<Gt(VICTR20)7Lex>,Trp53<tm1Tyj>/Trp53<+>

http://metadb.riken.jp/0011100I129S2SvPas129S5SvEvBrdMdm4GtVICTR207LexMdm4GtVICTR207LexTrp53tm1TyjTrp53Trp53tm1TyjTrp53Mdm4GtVICTR207Lex

preweaning lethality, complete penetrance_Mdm4<Gt(VICTR20)7Lex>/Mdm4<Gt(VICTR20)7Lex>,Trp53<tm1Tyj>/Trp53<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformed mouse 3T3 cell double minute 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:107934
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mdm4<Gt(VICTR20)7Lex>/Mdm4<Gt(VICTR20)7Lex>,Trp53<tm1Tyj>/Trp53<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Tyj>|Trp53<+>|Mdm4<Gt(VICTR20)7Lex>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S5/SvEvBrd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete preweaning lethality
  http://purl.obolibrary.org/obo/MP_0011100

文献

http://purl.org/net/cito/citesAsAuthority

• Domenico. Migliorini, et.al., Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development., Molecular and cellular biology, 2002, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/12101245