prenatal lethality, incomplete penetrance_Trp53<tm1Tyj>/Trp53<+>,Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>

http://metadb.riken.jp/0011101I129S2SvPas129S6SvEvTacC57BL6JTrp53tm1TyjTrp53Trp53bp2tm1XluTrp53bp2tm1XluTrp53Trp53tm1TyjTrp53bp2tm1Xlu

prenatal lethality, incomplete penetrance_Trp53<tm1Tyj>/Trp53<+>,Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53 binding protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2138319
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Tyj>/Trp53<+>,Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<+>|Trp53<tm1Tyj>|Trp53bp2<tm1Xlu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial prenatal lethality
  http://purl.obolibrary.org/obo/MP_0011101

文献

http://purl.org/net/cito/citesAsAuthority

• Virginie. Vives, et.al., ASPP2 is a haploinsufficient tumor suppressor that cooperates with p53 to suppress tumor growth., Genes & development, 2006, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/16702401