embryonic lethality during organogenesis, incomplete penetrance_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>

http://metadb.riken.jp/0011108I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa

embryonic lethality during organogenesis, incomplete penetrance_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• thrombomodulin
  http://metadb.riken.jp/db/mgi_rdf/MGI:98736
• transgene insertion 1, Masashi Yanagisawa
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450309

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Thbd<tm2Rdr>|Thbd<tm2Wlr>|Tg(Tek-cre)1Ywa

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011108

文献

http://purl.org/net/cito/citesAsAuthority

• B. Isermann, et.al., Endothelium-specific loss of murine thrombomodulin disrupts the protein C anticoagulant pathway and causes juvenile-onset thrombosis., The Journal of clinical investigation, 2001, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/11518727