B. Isermann, et.al., Endothelium-specific loss of murine thrombomodulin disrupts the protein C anticoagulant pathway and causes juvenile-onset thrombosis., The Journal of clinical investigation, 2001, 108

http://rdf.ncbi.nlm.nih.gov/pubmed/11518727

B. Isermann, et.al., Endothelium-specific loss of murine thrombomodulin disrupts the protein C anticoagulant pathway and causes juvenile-onset thrombosis., The Journal of clinical investigation, 2001, 108

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Thbd<tm2Wlr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2158819

class

http://purl.org/net/cito/citesAsAuthority

• Thbd<tm2Wlr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2158819

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• slow postnatal weight gain_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0008489I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• lung hemorrhage_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0001182I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• abnormal thrombosis_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0005048I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• decreased body size_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0001265I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• abnormal blood coagulation_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0002551I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• increased spleen weight_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0004952I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• pallor_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0003717I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• decreased body weight_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0001262I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• gastrointestinal hemorrhage_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0000465I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• priapism_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0003415I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• intracerebral hemorrhage_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0001916I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• abnormal acute phase protein level_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0010211I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• cardiac fibrosis_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0003141I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• premature death_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0002083I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• thrombocytopenia_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0003179I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• lethality throughout fetal growth and development, incomplete penetrance_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0011109I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• hemothorax_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0005243I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• abnormal placental thrombosis_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0020407I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• pulmonary hypertension_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0003548I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• hematuria_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0005161I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• increased circulating interleukin-6 level_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0008596I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• increased heart right ventricle weight_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0003913I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• increased megakaryocyte cell number_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0008254I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• liver hemorrhage_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0003888I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• abnormal lung morphology_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0001175I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• skin hemorrhage_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0011514I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• enlarged heart_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0000274I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• increased heart weight_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0002833I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• embryonic lethality during organogenesis, incomplete penetrance_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0011108I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa
• abnormal liver morphology_Tg(Tek-cre)1Ywa/0,Thbd<tm2Rdr>/Thbd<tm2Wlr>
  http://metadb.riken.jp/0000598I129S2SvPasC57BL6SJLTgTekcre1Ywa0Thbdtm2RdrThbdtm2WlrThbdtm2RdrThbdtm2WlrTgTekcre1Ywa

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]

BRC マウスの系統

http://purl.org/net/cito/citesAsAuthority

• B6.Cg-Tg(Tek-cre)1Ywa
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC04495

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]