embryonic lethality during organogenesis, incomplete penetrance_Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Isl1<tm1(cre)Sev>/Isl1<+>

http://metadb.riken.jp/0011108I129SSvFgf8tm2MoonFgf8tm1MrcIsl1tm1creSevIsl1Isl1Isl1tm1creSevFgf8tm2MoonFgf8tm1Mrc

embryonic lethality during organogenesis, incomplete penetrance_Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Isl1<tm1(cre)Sev>/Isl1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• fibroblast growth factor 8
  http://metadb.riken.jp/db/mgi_rdf/MGI:99604
• ISL1 transcription factor, LIM/homeodomain
  http://metadb.riken.jp/db/mgi_rdf/MGI:101791

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Isl1<tm1(cre)Sev>/Isl1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Isl1<+>|Isl1<tm1(cre)Sev>|Fgf8<tm2Moon>|Fgf8<tm1Mrc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/Sv

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial embryonic lethality during organogenesis
  http://purl.obolibrary.org/obo/MP_0011108

文献

http://purl.org/net/cito/citesAsAuthority

• Eon Joo. Park, et.al., Required, tissue-specific roles for Fgf8 in outflow tract formation and remodeling., Development (Cambridge, England), 2006, 133
  http://rdf.ncbi.nlm.nih.gov/pubmed/16720879