Eon Joo. Park, et.al., Required, tissue-specific roles for Fgf8 in outflow tract formation and remodeling., Development (Cambridge, England), 2006, 133

http://rdf.ncbi.nlm.nih.gov/pubmed/16720879

Eon Joo. Park, et.al., Required, tissue-specific roles for Fgf8 in outflow tract formation and remodeling., Development (Cambridge, England), 2006, 133

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Fgf8<tm2Moon>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3639320

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• bicuspid aortic valve_Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Mesp1<tm2(cre)Ysa>/Mesp1<+>
  http://metadb.riken.jp/0010484IC57BL6CBAFgf8tm2MoonFgf8tm1MrcMesp1tm2creYsaMesp1Fgf8tm2MoonFgf8tm1MrcMesp1Mesp1tm2creYsa
• transposition of great arteries_Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Mesp1<tm2(cre)Ysa>/Mesp1<+>
  http://metadb.riken.jp/0004110IC57BL6CBAFgf8tm2MoonFgf8tm1MrcMesp1tm2creYsaMesp1Fgf8tm2MoonFgf8tm1MrcMesp1Mesp1tm2creYsa
• abnormal truncus arteriosus septation_Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0010454I129SSvFgf8tm2MoonFgf8tm1MrcIsl1tm1creSevIsl1Isl1Isl1tm1creSevFgf8tm2MoonFgf8tm1Mrc
• decreased cell proliferation_Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Mesp1<tm2(cre)Ysa>/Mesp1<+>
  http://metadb.riken.jp/0000352IC57BL6CBAFgf8tm2MoonFgf8tm1MrcMesp1tm2creYsaMesp1Fgf8tm2MoonFgf8tm1MrcMesp1Mesp1tm2creYsa
• transposition of great arteries_Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Tg(Mef2c-cre)2Blk/0
  http://metadb.riken.jp/0004110NSFgf8tm2MoonFgf8tm1MrcTgMef2ccre2Blk0TgMef2ccre2BlkFgf8tm2MoonFgf8tm1Mrc
• small pharyngeal arch_Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0006346I129SSvFgf8tm2MoonFgf8tm1MrcIsl1tm1creSevIsl1Isl1Isl1tm1creSevFgf8tm2MoonFgf8tm1Mrc
• double outlet right ventricle_Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Tg(Mef2c-cre)2Blk/0
  http://metadb.riken.jp/0000284NSFgf8tm2MoonFgf8tm1MrcTgMef2ccre2Blk0TgMef2ccre2BlkFgf8tm2MoonFgf8tm1Mrc
• embryonic lethality during organogenesis, incomplete penetrance_Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0011108I129SSvFgf8tm2MoonFgf8tm1MrcIsl1tm1creSevIsl1Isl1Isl1tm1creSevFgf8tm2MoonFgf8tm1Mrc
• common atrium_Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Mesp1<tm2(cre)Ysa>/Mesp1<+>
  http://metadb.riken.jp/0010406IC57BL6CBAFgf8tm2MoonFgf8tm1MrcMesp1tm2creYsaMesp1Fgf8tm2MoonFgf8tm1MrcMesp1Mesp1tm2creYsa
• embryonic lethality during organogenesis, incomplete penetrance_Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Mesp1<tm2(cre)Ysa>/Mesp1<+>
  http://metadb.riken.jp/0011108IC57BL6CBAFgf8tm2MoonFgf8tm1MrcMesp1tm2creYsaMesp1Fgf8tm2MoonFgf8tm1MrcMesp1Mesp1tm2creYsa
• edema_Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Mesp1<tm2(cre)Ysa>/Mesp1<+>
  http://metadb.riken.jp/0001785IC57BL6CBAFgf8tm2MoonFgf8tm1MrcMesp1tm2creYsaMesp1Fgf8tm2MoonFgf8tm1MrcMesp1Mesp1tm2creYsa
• abnormal heart tube morphology_Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Mesp1<tm2(cre)Ysa>/Mesp1<+>
  http://metadb.riken.jp/0000270IC57BL6CBAFgf8tm2MoonFgf8tm1MrcMesp1tm2creYsaMesp1Fgf8tm2MoonFgf8tm1MrcMesp1Mesp1tm2creYsa
• common ventricle_Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Mesp1<tm2(cre)Ysa>/Mesp1<+>
  http://metadb.riken.jp/0010432IC57BL6CBAFgf8tm2MoonFgf8tm1MrcMesp1tm2creYsaMesp1Fgf8tm2MoonFgf8tm1MrcMesp1Mesp1tm2creYsa
• abnormal cardiac outflow tract development_Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Mesp1<tm2(cre)Ysa>/Mesp1<+>
  http://metadb.riken.jp/0006126IC57BL6CBAFgf8tm2MoonFgf8tm1MrcMesp1tm2creYsaMesp1Fgf8tm2MoonFgf8tm1MrcMesp1Mesp1tm2creYsa
• bicuspid pulmonary valve_Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Mesp1<tm2(cre)Ysa>/Mesp1<+>
  http://metadb.riken.jp/0010527IC57BL6CBAFgf8tm2MoonFgf8tm1MrcMesp1tm2creYsaMesp1Fgf8tm2MoonFgf8tm1MrcMesp1Mesp1tm2creYsa
• increased apoptosis_Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0006042I129SSvFgf8tm2MoonFgf8tm1MrcIsl1tm1creSevIsl1Isl1Isl1tm1creSevFgf8tm2MoonFgf8tm1Mrc
• increased apoptosis_Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Mesp1<tm2(cre)Ysa>/Mesp1<+>
  http://metadb.riken.jp/0006042IC57BL6CBAFgf8tm2MoonFgf8tm1MrcMesp1tm2creYsaMesp1Fgf8tm2MoonFgf8tm1MrcMesp1Mesp1tm2creYsa
• pericardial effusion_Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Mesp1<tm2(cre)Ysa>/Mesp1<+>
  http://metadb.riken.jp/0005312IC57BL6CBAFgf8tm2MoonFgf8tm1MrcMesp1tm2creYsaMesp1Fgf8tm2MoonFgf8tm1MrcMesp1Mesp1tm2creYsa
• persistent truncus arteriosis_Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0002633I129SSvFgf8tm2MoonFgf8tm1MrcIsl1tm1creSevIsl1Isl1Isl1tm1creSevFgf8tm2MoonFgf8tm1Mrc
• abnormal heart right ventricle morphology_Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0003920I129SSvFgf8tm2MoonFgf8tm1MrcIsl1tm1creSevIsl1Isl1Isl1tm1creSevFgf8tm2MoonFgf8tm1Mrc
• decreased heart right ventricle size_Fgf8<tm2Moon>/Fgf8<tm1Mrc>,Mesp1<tm2(cre)Ysa>/Mesp1<+>
  http://metadb.riken.jp/0003649IC57BL6CBAFgf8tm2MoonFgf8tm1MrcMesp1tm2creYsaMesp1Fgf8tm2MoonFgf8tm1MrcMesp1Mesp1tm2creYsa

class

http://purl.org/net/cito/citesAsAuthority

• Fgf8<tm2Moon>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3639320