increased erythroblast number_Flt3<tm1Dgg>/Flt3<+>,Kmt2a<tm1Clgr>/Kmt2a<+>

http://metadb.riken.jp/0011178I129S1Sv129X1SvJBALBcC57BL6JFlt3tm1DggFlt3Kmt2atm1ClgrKmt2aFlt3tm1DggKmt2atm1ClgrFlt3Kmt2a

increased erythroblast number_Flt3<tm1Dgg>/Flt3<+>,Kmt2a<tm1Clgr>/Kmt2a<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• FMS-like tyrosine kinase 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:95559
• lysine (K)-specific methyltransferase 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:96995

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Flt3<tm1Dgg>/Flt3<+>,Kmt2a<tm1Clgr>/Kmt2a<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Flt3<tm1Dgg>|Kmt2a<tm1Clgr>|Flt3<+>|Kmt2a<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased erythroblast number
  http://purl.obolibrary.org/obo/MP_0011178

文献

http://purl.org/net/cito/citesAsAuthority

• Nicholas A. Zorko, et.al., Mll partial tandem duplication and Flt3 internal tandem duplication in a double knock-in mouse recapitulates features of counterpart human acute myeloid leukemias., Blood, 2012, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/22674806