Nicholas A. Zorko, et.al., Mll partial tandem duplication and Flt3 internal tandem duplication in a double knock-in mouse recapitulates features of counterpart human acute myeloid leukemias., Blood, 2012, 120

http://rdf.ncbi.nlm.nih.gov/pubmed/22674806

Nicholas A. Zorko, et.al., Mll partial tandem duplication and Flt3 internal tandem duplication in a double knock-in mouse recapitulates features of counterpart human acute myeloid leukemias., Blood, 2012, 120

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• premature death_Flt3<tm1Dgg>/Flt3<tm1Dgg>,Kmt2a<tm1Clgr>/Kmt2a<+>
  http://metadb.riken.jp/0002083I129S1Sv129X1SvJBALBcC57BL6JFlt3tm1DggFlt3tm1DggKmt2atm1ClgrKmt2aFlt3tm1DggKmt2aKmt2atm1Clgr
• premature death_Flt3<tm1Dgg>/Flt3<+>,Kmt2a<tm1Clgr>/Kmt2a<+>
  http://metadb.riken.jp/0002083I129S1Sv129X1SvJBALBcC57BL6JFlt3tm1DggFlt3Kmt2atm1ClgrKmt2aFlt3tm1DggKmt2atm1ClgrFlt3Kmt2a
• increased leukocyte cell number_Flt3<tm1Dgg>/Flt3<tm1Dgg>,Kmt2a<tm1Clgr>/Kmt2a<+>
  http://metadb.riken.jp/0000218I129S1Sv129X1SvJBALBcC57BL6JFlt3tm1DggFlt3tm1DggKmt2atm1ClgrKmt2aFlt3tm1DggKmt2aKmt2atm1Clgr
• increased leukocyte cell number_Flt3<tm1Dgg>/Flt3<+>,Kmt2a<tm1Clgr>/Kmt2a<+>
  http://metadb.riken.jp/0000218I129S1Sv129X1SvJBALBcC57BL6JFlt3tm1DggFlt3Kmt2atm1ClgrKmt2aFlt3tm1DggKmt2atm1ClgrFlt3Kmt2a
• thrombocytopenia_Flt3<tm1Dgg>/Flt3<+>,Kmt2a<tm1Clgr>/Kmt2a<+>
  http://metadb.riken.jp/0003179I129S1Sv129X1SvJBALBcC57BL6JFlt3tm1DggFlt3Kmt2atm1ClgrKmt2aFlt3tm1DggKmt2atm1ClgrFlt3Kmt2a
• enlarged spleen_Flt3<tm1Dgg>/Flt3<tm1Dgg>,Kmt2a<tm1Clgr>/Kmt2a<+>
  http://metadb.riken.jp/0000691I129S1Sv129X1SvJBALBcC57BL6JFlt3tm1DggFlt3tm1DggKmt2atm1ClgrKmt2aFlt3tm1DggKmt2aKmt2atm1Clgr
• increased leukemia incidence_Flt3<tm1Dgg>/Flt3<tm1Dgg>,Kmt2a<tm1Clgr>/Kmt2a<+>
  http://metadb.riken.jp/0002026I129S1Sv129X1SvJBALBcC57BL6JFlt3tm1DggFlt3tm1DggKmt2atm1ClgrKmt2aFlt3tm1DggKmt2aKmt2atm1Clgr
• increased erythroblast number_Flt3<tm1Dgg>/Flt3<+>,Kmt2a<tm1Clgr>/Kmt2a<+>
  http://metadb.riken.jp/0011178I129S1Sv129X1SvJBALBcC57BL6JFlt3tm1DggFlt3Kmt2atm1ClgrKmt2aFlt3tm1DggKmt2atm1ClgrFlt3Kmt2a
• anemia_Flt3<tm1Dgg>/Flt3<+>,Kmt2a<tm1Clgr>/Kmt2a<+>
  http://metadb.riken.jp/0001577I129S1Sv129X1SvJBALBcC57BL6JFlt3tm1DggFlt3Kmt2atm1ClgrKmt2aFlt3tm1DggKmt2atm1ClgrFlt3Kmt2a
• enlarged spleen_Flt3<tm1Dgg>/Flt3<+>,Kmt2a<tm1Clgr>/Kmt2a<+>
  http://metadb.riken.jp/0000691I129S1Sv129X1SvJBALBcC57BL6JFlt3tm1DggFlt3Kmt2atm1ClgrKmt2aFlt3tm1DggKmt2atm1ClgrFlt3Kmt2a
• increased leukemia incidence_Flt3<tm1Dgg>/Flt3<+>,Kmt2a<tm1Clgr>/Kmt2a<+>
  http://metadb.riken.jp/0002026I129S1Sv129X1SvJBALBcC57BL6JFlt3tm1DggFlt3Kmt2atm1ClgrKmt2aFlt3tm1DggKmt2atm1ClgrFlt3Kmt2a