decreased circulating erythropoietin level_Epas1<tm1Mcs>/Epas1<tm1Mcs>,Vhl<tm1Jae>/Vhl<tm1Jae>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0

http://metadb.riken.jp/0011286I129S4SvJae129X1SvJCD1Epas1tm1McsEpas1tm1McsVhltm1JaeVhltm1JaeTgSp7tTAtetOEGFPcre1Amc0Vhltm1JaeEpas1tm1McsTgSp7tTAtetOEGFPcre1Amc

decreased circulating erythropoietin level_Epas1<tm1Mcs>/Epas1<tm1Mcs>,Vhl<tm1Jae>/Vhl<tm1Jae>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:3689349
• von Hippel-Lindau tumor suppressor
  http://metadb.riken.jp/db/mgi_rdf/MGI:103223
• endothelial PAS domain protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:109169

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Epas1<tm1Mcs>/Epas1<tm1Mcs>,Vhl<tm1Jae>/Vhl<tm1Jae>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Vhl<tm1Jae>|Epas1<tm1Mcs>|Tg(Sp7-tTA,tetO-EGFP/cre)1Amc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129X1/SvJ * CD-1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating erythropoietin level
  http://purl.obolibrary.org/obo/MP_0011286

文献

http://purl.org/net/cito/citesAsAuthority

• Erinn B. Rankin, et.al., The HIF signaling pathway in osteoblasts directly modulates erythropoiesis through the production of EPO., Cell, 2012, 149
  http://rdf.ncbi.nlm.nih.gov/pubmed/22464323