decreased nephron number_Pax2<1Neu>/Pax2<+>

http://metadb.riken.jp/0011290I102C57BL6Pax21NeuPax2Pax2Pax21Neu

decreased nephron number_Pax2<1Neu>/Pax2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• paired box 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97486

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pax2<1Neu>/Pax2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pax2<+>|Pax2<1Neu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 102 * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased nephron number
  http://purl.obolibrary.org/obo/MP_0011290

文献

http://purl.org/net/cito/citesAsAuthority

• S. Porteous, et.al., Primary renal hypoplasia in humans and mice with PAX2 mutations: evidence of increased apoptosis in fetal kidneys of Pax2(1Neu) +/- mutant mice., Human molecular genetics, 2000, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/10587573
• Maria Teresa. Discenza, et.al., WT1 is a modifier of the Pax2 mutant phenotype: cooperation and interaction between WT1 and Pax2., Oncogene, 2003, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/14603255