decreased nephron number_Jag1<tm1Frad>/Jag1<tm1Frad>,Tg(Six2-EGFP/cre)1Amc/0

http://metadb.riken.jp/0011290I129SvC57BL6CD1Jag1tm1FradJag1tm1FradTgSix2EGFPcre1Amc0TgSix2EGFPcre1AmcJag1tm1Frad

decreased nephron number_Jag1<tm1Frad>/Jag1<tm1Frad>,Tg(Six2-EGFP/cre)1Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• jagged 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1095416
• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:3845227

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Jag1<tm1Frad>/Jag1<tm1Frad>,Tg(Six2-EGFP/cre)1Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Six2-EGFP/cre)1Amc|Jag1<tm1Frad>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6 * CD-1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased nephron number
  http://purl.obolibrary.org/obo/MP_0011290

文献

http://purl.org/net/cito/citesAsAuthority

• Zhenyi. Liu, et.al., The extracellular domain of Notch2 increases its cell-surface abundance and ligand responsiveness during kidney development., Developmental cell, 2013, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/23806616