renal tubule atrophy_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0

http://metadb.riken.jp/0011346I129S1Sv129X1SvJC57BL6SJLIlktm1StarIlktm1StarTgNPHS2cre295Lbh0TgNPHS2cre295LbhIlktm1Star

renal tubule atrophy_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• integrin linked kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:1195267
• transgene insertion 295, Lawrence B Holzman
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450360

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(NPHS2-cre)295Lbh|Ilk<tm1Star>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• renal tubule atrophy
  http://purl.obolibrary.org/obo/MP_0011346

文献

http://purl.org/net/cito/citesAsAuthority

• Chiraz. El-Aouni, et.al., Podocyte-specific deletion of integrin-linked kinase results in severe glomerular basement membrane alterations and progressive glomerulosclerosis., Journal of the American Society of Nephrology : JASN, 2006, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/16611717