Chiraz. El-Aouni, et.al., Podocyte-specific deletion of integrin-linked kinase results in severe glomerular basement membrane alterations and progressive glomerulosclerosis., Journal of the American Society of Nephrology : JASN, 2006, 17

http://rdf.ncbi.nlm.nih.gov/pubmed/16611717

Chiraz. El-Aouni, et.al., Podocyte-specific deletion of integrin-linked kinase results in severe glomerular basement membrane alterations and progressive glomerulosclerosis., Journal of the American Society of Nephrology : JASN, 2006, 17

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal podocyte morphology_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0
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• increased urine protein level_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0002962I129S1Sv129X1SvJC57BL6SJLIlktm1StarIlktm1StarTgNPHS2cre295Lbh0TgNPHS2cre295LbhIlktm1Star
• premature death_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0002083I129S1Sv129X1SvJC57BL6SJLIlktm1StarIlktm1StarTgNPHS2cre295Lbh0TgNPHS2cre295LbhIlktm1Star
• detached podocyte_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0011869I129S1Sv129X1SvJC57BL6SJLIlktm1StarIlktm1StarTgNPHS2cre295Lbh0TgNPHS2cre295LbhIlktm1Star
• glomerular crescent_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0011506I129S1Sv129X1SvJC57BL6SJLIlktm1StarIlktm1StarTgNPHS2cre295Lbh0TgNPHS2cre295LbhIlktm1Star
• tubulointerstitial nephritis_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0011405I129S1Sv129X1SvJC57BL6SJLIlktm1StarIlktm1StarTgNPHS2cre295Lbh0TgNPHS2cre295LbhIlktm1Star
• abnormal glomerular capillary morphology_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0011320I129S1Sv129X1SvJC57BL6SJLIlktm1StarIlktm1StarTgNPHS2cre295Lbh0TgNPHS2cre295LbhIlktm1Star
• abnormal renal glomerulus basement membrane morphology_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0011348I129S1Sv129X1SvJC57BL6SJLIlktm1StarIlktm1StarTgNPHS2cre295Lbh0TgNPHS2cre295LbhIlktm1Star
• increased renal glomerulus basement membrane thickness_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0011409I129S1Sv129X1SvJC57BL6SJLIlktm1StarIlktm1StarTgNPHS2cre295Lbh0TgNPHS2cre295LbhIlktm1Star
• albuminuria_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0002871I129S1Sv129X1SvJC57BL6SJLIlktm1StarIlktm1StarTgNPHS2cre295Lbh0TgNPHS2cre295LbhIlktm1Star
• podocyte foot process effacement_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0008140I129S1Sv129X1SvJC57BL6SJLIlktm1StarIlktm1StarTgNPHS2cre295Lbh0TgNPHS2cre295LbhIlktm1Star
• abnormal podocyte slit diaphragm morphology_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0008060I129S1Sv129X1SvJC57BL6SJLIlktm1StarIlktm1StarTgNPHS2cre295Lbh0TgNPHS2cre295LbhIlktm1Star
• podocyte microvillus transformation_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0011868I129S1Sv129X1SvJC57BL6SJLIlktm1StarIlktm1StarTgNPHS2cre295Lbh0TgNPHS2cre295LbhIlktm1Star
• renal tubule atrophy_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0011346I129S1Sv129X1SvJC57BL6SJLIlktm1StarIlktm1StarTgNPHS2cre295Lbh0TgNPHS2cre295LbhIlktm1Star
• kidney failure_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0003606I129S1Sv129X1SvJC57BL6SJLIlktm1StarIlktm1StarTgNPHS2cre295Lbh0TgNPHS2cre295LbhIlktm1Star
• glomerulosclerosis_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0005264I129S1Sv129X1SvJC57BL6SJLIlktm1StarIlktm1StarTgNPHS2cre295Lbh0TgNPHS2cre295LbhIlktm1Star
• increased circulating cholesterol level_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0005178I129S1Sv129X1SvJC57BL6SJLIlktm1StarIlktm1StarTgNPHS2cre295Lbh0TgNPHS2cre295LbhIlktm1Star
• renal interstitial fibrosis_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0003215I129S1Sv129X1SvJC57BL6SJLIlktm1StarIlktm1StarTgNPHS2cre295Lbh0TgNPHS2cre295LbhIlktm1Star
• expanded mesangial matrix_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0011353I129S1Sv129X1SvJC57BL6SJLIlktm1StarIlktm1StarTgNPHS2cre295Lbh0TgNPHS2cre295LbhIlktm1Star
• renal glomerular synechia_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0011483I129S1Sv129X1SvJC57BL6SJLIlktm1StarIlktm1StarTgNPHS2cre295Lbh0TgNPHS2cre295LbhIlktm1Star
• increased blood urea nitrogen level_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0005565I129S1Sv129X1SvJC57BL6SJLIlktm1StarIlktm1StarTgNPHS2cre295Lbh0TgNPHS2cre295LbhIlktm1Star
• abnormal kidney morphology_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0002135I129S1Sv129X1SvJC57BL6SJLIlktm1StarIlktm1StarTgNPHS2cre295Lbh0TgNPHS2cre295LbhIlktm1Star
• abnormal glomerular filtration barrier function_Ilk<tm1Star>/Ilk<tm1Star>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0011856I129S1Sv129X1SvJC57BL6SJLIlktm1StarIlktm1StarTgNPHS2cre295Lbh0TgNPHS2cre295LbhIlktm1Star