abnormal renal glomerulus basement membrane morphology_Col4a3<tm1Jhm>/Col4a3<tm1Jhm>,Tg(Nphs1-rtTA*3G)8Jhm/0,Tg(tetO-COL4A3/Col4a3)#aJhm/0

http://metadb.riken.jp/0011348I129S1Sv129X1SvJC57BL6CBACol4a3tm1JhmCol4a3tm1JhmTgNphs1rtTA3G8Jhm0TgtetOCOL4A3Col4a3aJhm0TgNphs1rtTA3G8JhmTgtetOCOL4A3Col4a3aJhmCol4a3tm1Jhm

abnormal renal glomerulus basement membrane morphology_Col4a3<tm1Jhm>/Col4a3<tm1Jhm>,Tg(Nphs1-rtTA*3G)8Jhm/0,Tg(tetO-COL4A3/Col4a3)#aJhm/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion #a, Jeffrey H Miner
  http://metadb.riken.jp/db/mgi_rdf/MGI:5559178
• collagen, type IV, alpha 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:104688
• transgene insertion 8, Jeffrey H Miner
  http://metadb.riken.jp/db/mgi_rdf/MGI:5559176

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Col4a3<tm1Jhm>/Col4a3<tm1Jhm>,Tg(Nphs1-rtTA*3G)8Jhm/0,Tg(tetO-COL4A3/Col4a3)#aJhm/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Nphs1-rtTA*3G)8Jhm|Tg(tetO-COL4A3/Col4a3)#aJhm|Col4a3<tm1Jhm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal renal glomerulus basement membrane morphology
  http://purl.obolibrary.org/obo/MP_0011348

文献

http://purl.org/net/cito/citesAsAuthority

• Xiaobo. Lin, et.al., Feasibility of repairing glomerular basement membrane defects in Alport syndrome., Journal of the American Society of Nephrology : JASN, 2014, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/24262794