Xiaobo. Lin, et.al., Feasibility of repairing glomerular basement membrane defects in Alport syndrome., Journal of the American Society of Nephrology : JASN, 2014, 25

http://rdf.ncbi.nlm.nih.gov/pubmed/24262794

Xiaobo. Lin, et.al., Feasibility of repairing glomerular basement membrane defects in Alport syndrome., Journal of the American Society of Nephrology : JASN, 2014, 25

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Nphs1-rtTA*3G)8Jhm
  http://metadb.riken.jp/db/mgi_rdf/MGI:5559153
• Tg(tetO-COL4A3/Col4a3)#aJhm
  http://metadb.riken.jp/db/mgi_rdf/MGI:5559154

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased renal glomerulus basement membrane thickness_Col4a3<tm1Jhm>/Col4a3<tm1Jhm>,Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/Gt(ROSA)26Sor<+>,Tg(tetO-COL4A3/Col4a3)#aJhm/0
  http://metadb.riken.jp/0011409I129S1Sv129X1SvJC57BL6CBACol4a3tm1JhmCol4a3tm1JhmGtROSA26Sortm1rtTAEGFPNagyGtROSA26SorTgtetOCOL4A3Col4a3aJhm0GtROSA26Sortm1rtTAEGFPNagyTgtetOCOL4A3Col4a3aJhmGtROSA26SorCol4a3tm1Jhm
• abnormal podocyte foot process morphology_Col4a3<tm1Jhm>/Col4a3<tm1Jhm>
  http://metadb.riken.jp/0008059I129S1Sv129X1SvJCol4a3tm1JhmCol4a3tm1JhmCol4a3tm1Jhm
• increased renal glomerulus basement membrane thickness_Col4a3<tm1Jhm>/Col4a3<tm1Jhm>
  http://metadb.riken.jp/0011409I129S1Sv129X1SvJCol4a3tm1JhmCol4a3tm1JhmCol4a3tm1Jhm
• abnormal renal glomerulus basement membrane morphology_Col4a3<tm1Jhm>/Col4a3<tm1Jhm>,Tg(Nphs1-rtTA*3G)8Jhm/0,Tg(tetO-COL4A3/Col4a3)#aJhm/0
  http://metadb.riken.jp/0011348I129S1Sv129X1SvJC57BL6CBACol4a3tm1JhmCol4a3tm1JhmTgNphs1rtTA3G8Jhm0TgtetOCOL4A3Col4a3aJhm0TgNphs1rtTA3G8JhmTgtetOCOL4A3Col4a3aJhmCol4a3tm1Jhm
• glomerulosclerosis_Col4a3<tm1Jhm>/Col4a3<tm1Jhm>
  http://metadb.riken.jp/0005264I129S1Sv129X1SvJCol4a3tm1JhmCol4a3tm1JhmCol4a3tm1Jhm
• abnormal podocyte foot process morphology_Col4a3<tm1Jhm>/Col4a3<tm1Jhm>,Tg(Nphs1-rtTA*3G)8Jhm/0,Tg(tetO-COL4A3/Col4a3)#aJhm/0
  http://metadb.riken.jp/0008059I129S1Sv129X1SvJC57BL6CBACol4a3tm1JhmCol4a3tm1JhmTgNphs1rtTA3G8Jhm0TgtetOCOL4A3Col4a3aJhm0TgNphs1rtTA3G8JhmTgtetOCOL4A3Col4a3aJhmCol4a3tm1Jhm
• abnormal renal glomerulus basement membrane morphology_Col4a3<tm1Jhm>/Col4a3<tm1Jhm>
  http://metadb.riken.jp/0011348I129S1Sv129X1SvJCol4a3tm1JhmCol4a3tm1JhmCol4a3tm1Jhm
• renal cast_Col4a3<tm1Jhm>/Col4a3<tm1Jhm>
  http://metadb.riken.jp/0011402I129S1Sv129X1SvJCol4a3tm1JhmCol4a3tm1JhmCol4a3tm1Jhm
• increased urine protein level_Col4a3<tm1Jhm>/Col4a3<tm1Jhm>
  http://metadb.riken.jp/0002962I129S1Sv129X1SvJCol4a3tm1JhmCol4a3tm1JhmCol4a3tm1Jhm
• premature death_Col4a3<tm1Jhm>/Col4a3<tm1Jhm>
  http://metadb.riken.jp/0002083I129S1Sv129X1SvJCol4a3tm1JhmCol4a3tm1JhmCol4a3tm1Jhm
• increased renal glomerulus basement membrane thickness_Col4a3<tm1Jhm>/Col4a3<tm1Jhm>,Tg(Nphs1-rtTA*3G)8Jhm/0,Tg(tetO-COL4A3/Col4a3)#aJhm/0
  http://metadb.riken.jp/0011409I129S1Sv129X1SvJC57BL6CBACol4a3tm1JhmCol4a3tm1JhmTgNphs1rtTA3G8Jhm0TgtetOCOL4A3Col4a3aJhm0TgNphs1rtTA3G8JhmTgtetOCOL4A3Col4a3aJhmCol4a3tm1Jhm

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Nphs1-rtTA*3G)8Jhm
  http://metadb.riken.jp/db/mgi_rdf/MGI:5559153
• Tg(tetO-COL4A3/Col4a3)#aJhm
  http://metadb.riken.jp/db/mgi_rdf/MGI:5559154