absent metanephric mesenchyme_Gt(ROSA)26Sor<tm2(Notch2)Ryn>/Gt(ROSA)26Sor<+>,Six2<tm1(tTA,tetO-EGFP/cre)Amc>/Six2<+>

http://metadb.riken.jp/0011387I129Sv129P2OlaHsdC57BL6JGtROSA26Sortm2Notch2RynGtROSA26SorSix2tm1tTAtetOEGFPcreAmcSix2GtROSA26Sortm2Notch2RynGtROSA26SorSix2tm1tTAtetOEGFPcreAmcSix2

absent metanephric mesenchyme_Gt(ROSA)26Sor<tm2(Notch2)Ryn>/Gt(ROSA)26Sor<+>,Six2<tm1(tTA,tetO-EGFP/cre)Amc>/Six2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• sine oculis-related homeobox 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:102778
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm2(Notch2)Ryn>/Gt(ROSA)26Sor<+>,Six2<tm1(tTA,tetO-EGFP/cre)Amc>/Six2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm2(Notch2)Ryn>|Gt(ROSA)26Sor<+>|Six2<tm1(tTA,tetO-EGFP/cre)Amc>|Six2<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129P2/OlaHsd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• absent metanephric mesenchyme
  http://purl.obolibrary.org/obo/MP_0011387

文献

http://purl.org/net/cito/citesAsAuthority

• Sayoko. Fujimura, et.al., Notch2 activation in the embryonic kidney depletes nephron progenitors., Journal of the American Society of Nephrology : JASN, 2010, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/20299358