increased fetal cardiomyocyte proliferation_Gt(ROSA)26Sor<tm1.1(CAG-Mirc20)Eem>/Gt(ROSA)26Sor<+>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>

http://metadb.riken.jp/0011394I129S7SvEvBrdC57BL6GtROSA26Sortm11CAGMirc20EemGtROSA26SorNkx25tm1creRjsNkx25Nkx25tm1creRjsNkx25GtROSA26Sortm11CAGMirc20EemGtROSA26Sor

increased fetal cardiomyocyte proliferation_Gt(ROSA)26Sor<tm1.1(CAG-Mirc20)Eem>/Gt(ROSA)26Sor<+>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• NK2 homeobox 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:97350

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1.1(CAG-Mirc20)Eem>/Gt(ROSA)26Sor<+>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nkx2-5<tm1(cre)Rjs>|Nkx2-5<+>|Gt(ROSA)26Sor<tm1.1(CAG-Mirc20)Eem>|Gt(ROSA)26Sor<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased fetal cardiomyocyte proliferation
  http://purl.obolibrary.org/obo/MP_0011394

文献

http://purl.org/net/cito/citesAsAuthority

• Ying. Tian, et.al., A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice., Science translational medicine, 2015, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/25787764