increased kidney cell proliferation_Pkd1<tm1.1Djmp>/Pkd1<tm1.2Djmp>,Tg(Cdh16-cre/ERT2)F427Djmp/0

http://metadb.riken.jp/0011440I129P2OlaHsdC57BL6C57BL6NCrlFVBNPkd1tm11DjmpPkd1tm12DjmpTgCdh16creERT2F427Djmp0Pkd1tm11DjmpTgCdh16creERT2F427DjmpPkd1tm12Djmp

increased kidney cell proliferation_Pkd1<tm1.1Djmp>/Pkd1<tm1.2Djmp>,Tg(Cdh16-cre/ERT2)F427Djmp/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• polycystic kidney disease 1 homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:97603
• transgene insertion F427, Dorien JM Peters
  http://metadb.riken.jp/db/mgi_rdf/MGI:3641107

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pkd1<tm1.1Djmp>/Pkd1<tm1.2Djmp>,Tg(Cdh16-cre/ERT2)F427Djmp/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pkd1<tm1.1Djmp>|Tg(Cdh16-cre/ERT2)F427Djmp|Pkd1<tm1.2Djmp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * C57BL/6NCrl * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased kidney cell proliferation
  http://purl.obolibrary.org/obo/MP_0011440

文献

http://purl.org/net/cito/citesAsAuthority

• Irma S. Lantinga-van Leeuwen, et.al., Kidney-specific inactivation of the Pkd1 gene induces rapid cyst formation in developing kidneys and a slow onset of disease in adult mice., Human molecular genetics, 2007, 16
  http://rdf.ncbi.nlm.nih.gov/pubmed/17932118