Irma S. Lantinga-van Leeuwen, et.al., Kidney-specific inactivation of the Pkd1 gene induces rapid cyst formation in developing kidneys and a slow onset of disease in adult mice., Human molecular genetics, 2007, 16

http://rdf.ncbi.nlm.nih.gov/pubmed/17932118

Irma S. Lantinga-van Leeuwen, et.al., Kidney-specific inactivation of the Pkd1 gene induces rapid cyst formation in developing kidneys and a slow onset of disease in adult mice., Human molecular genetics, 2007, 16

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pkd1<tm1.2Djmp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3771608

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased kidney cell proliferation_Pkd1<tm1.1Djmp>/Pkd1<tm1.2Djmp>,Tg(Cdh16-cre/ERT2)F427Djmp/0
  http://metadb.riken.jp/0011440I129P2OlaHsdC57BL6C57BL6NCrlFVBNPkd1tm11DjmpPkd1tm12DjmpTgCdh16creERT2F427Djmp0Pkd1tm11DjmpTgCdh16creERT2F427DjmpPkd1tm12Djmp
• dilated renal tubules_Pkd1<tm1.1Djmp>/Pkd1<tm1.2Djmp>,Tg(Cdh16-cre/ERT2)F427Djmp/0
  http://metadb.riken.jp/0002705I129P2OlaHsdC57BL6C57BL6NCrlFVBNPkd1tm11DjmpPkd1tm12DjmpTgCdh16creERT2F427Djmp0Pkd1tm11DjmpTgCdh16creERT2F427DjmpPkd1tm12Djmp
• pale kidney_Pkd1<tm1.1Djmp>/Pkd1<tm1.2Djmp>,Tg(Cdh16-cre/ERT2)F427Djmp/0
  http://metadb.riken.jp/0004969I129P2OlaHsdC57BL6C57BL6NCrlFVBNPkd1tm11DjmpPkd1tm12DjmpTgCdh16creERT2F427Djmp0Pkd1tm11DjmpTgCdh16creERT2F427DjmpPkd1tm12Djmp
• increased kidney weight_Pkd1<tm1.1Djmp>/Pkd1<tm1.2Djmp>,Tg(Cdh16-cre/ERT2)F427Djmp/0
  http://metadb.riken.jp/0003917I129P2OlaHsdC57BL6C57BL6NCrlFVBNPkd1tm11DjmpPkd1tm12DjmpTgCdh16creERT2F427Djmp0Pkd1tm11DjmpTgCdh16creERT2F427DjmpPkd1tm12Djmp
• liver cysts_Pkd1<tm1.1Djmp>/Pkd1<tm1.2Djmp>,Tg(Cdh16-cre/ERT2)F427Djmp/0
  http://metadb.riken.jp/0003327I129P2OlaHsdC57BL6C57BL6NCrlFVBNPkd1tm11DjmpPkd1tm12DjmpTgCdh16creERT2F427Djmp0Pkd1tm11DjmpTgCdh16creERT2F427DjmpPkd1tm12Djmp
• kidney cysts_Pkd1<tm1.1Djmp>/Pkd1<tm1.2Djmp>,Tg(Cdh16-cre/ERT2)F427Djmp/0
  http://metadb.riken.jp/0003675I129P2OlaHsdC57BL6C57BL6NCrlFVBNPkd1tm11DjmpPkd1tm12DjmpTgCdh16creERT2F427Djmp0Pkd1tm11DjmpTgCdh16creERT2F427DjmpPkd1tm12Djmp
• polycystic kidney_Pkd1<tm1.1Djmp>/Pkd1<tm1.2Djmp>,Tg(Cdh16-cre/ERT2)F427Djmp/0
  http://metadb.riken.jp/0008528I129P2OlaHsdC57BL6C57BL6NCrlFVBNPkd1tm11DjmpPkd1tm12DjmpTgCdh16creERT2F427Djmp0Pkd1tm11DjmpTgCdh16creERT2F427DjmpPkd1tm12Djmp
• prenatal lethality, complete penetrance_Pkd1<tm1.2Djmp>/Pkd1<tm1.2Djmp>
  http://metadb.riken.jp/0011091I129P2OlaHsdFVBNPkd1tm12DjmpPkd1tm12DjmpPkd1tm12Djmp
• kidney cysts_Pkd1<tm1.1Djmp>/Pkd1<tm1.1Djmp>,Tg(Cdh16-cre/ERT2)F427Djmp/0
  http://metadb.riken.jp/0003675I129P2OlaHsdC57BL6C57BL6NCrlFVBNPkd1tm11DjmpPkd1tm11DjmpTgCdh16creERT2F427Djmp0TgCdh16creERT2F427DjmpPkd1tm11Djmp
• increased kidney cell proliferation_Pkd1<tm1.2Djmp>/Pkd1<+>
  http://metadb.riken.jp/0011440I129P2OlaHsdFVBNPkd1tm12DjmpPkd1Pkd1tm12DjmpPkd1

class

http://purl.org/net/cito/citesAsAuthority

• Pkd1<tm1.2Djmp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3771608