increased kidney cell proliferation_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Nes-cre)Wme/0

http://metadb.riken.jp/0011440I129S4SvJaeC57BL6CBAPkd1tm2GggPkd1tm2GggTgNescreWme0TgNescreWmePkd1tm2Ggg

increased kidney cell proliferation_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Nes-cre)Wme/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• polycystic kidney disease 1 homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:97603
• transgene insertion, Werner Muller
  http://metadb.riken.jp/db/mgi_rdf/MGI:4412412

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Nes-cre)Wme/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Nes-cre)Wme|Pkd1<tm2Ggg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased kidney cell proliferation
  http://purl.obolibrary.org/obo/MP_0011440

文献

http://purl.org/net/cito/citesAsAuthority

• Jonathan M. Shillingford, et.al., Rapamycin ameliorates PKD resulting from conditional inactivation of Pkd1., Journal of the American Society of Nephrology : JASN, 2010, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/20075061