Jonathan M. Shillingford, et.al., Rapamycin ameliorates PKD resulting from conditional inactivation of Pkd1., Journal of the American Society of Nephrology : JASN, 2010, 21

http://rdf.ncbi.nlm.nih.gov/pubmed/20075061

Jonathan M. Shillingford, et.al., Rapamycin ameliorates PKD resulting from conditional inactivation of Pkd1., Journal of the American Society of Nephrology : JASN, 2010, 21

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased kidney cell proliferation_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Nes-cre)Wme/0
  http://metadb.riken.jp/0011440I129S4SvJaeC57BL6CBAPkd1tm2GggPkd1tm2GggTgNescreWme0TgNescreWmePkd1tm2Ggg
• increased blood urea nitrogen level_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Nes-cre)Wme/0
  http://metadb.riken.jp/0005565I129S4SvJaeC57BL6CBAPkd1tm2GggPkd1tm2GggTgNescreWme0TgNescreWmePkd1tm2Ggg
• enlarged kidney_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Nes-cre)Wme/0
  http://metadb.riken.jp/0003068I129S4SvJaeC57BL6CBAPkd1tm2GggPkd1tm2GggTgNescreWme0TgNescreWmePkd1tm2Ggg
• abnormal kidney morphology_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Nes-cre)Wme/0
  http://metadb.riken.jp/0002135I129S4SvJaeC57BL6CBAPkd1tm2GggPkd1tm2GggTgNescreWme0TgNescreWmePkd1tm2Ggg
• increased kidney apoptosis_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Nes-cre)Wme/0
  http://metadb.riken.jp/0011368I129S4SvJaeC57BL6CBAPkd1tm2GggPkd1tm2GggTgNescreWme0TgNescreWmePkd1tm2Ggg
• renal fibrosis_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Nes-cre)Wme/0
  http://metadb.riken.jp/0003985I129S4SvJaeC57BL6CBAPkd1tm2GggPkd1tm2GggTgNescreWme0TgNescreWmePkd1tm2Ggg
• kidney cysts_Pkd1<tm2Ggg>/Pkd1<tm2Ggg>,Tg(Nes-cre)Wme/0
  http://metadb.riken.jp/0003675I129S4SvJaeC57BL6CBAPkd1tm2GggPkd1tm2GggTgNescreWme0TgNescreWmePkd1tm2Ggg