decreased dopaminergic neuron number_En1<tm1Gld>/En1<tm1Gld>,En2<tm1Alj>/En2<tm1Alj>

http://metadb.riken.jp/0011448I129SSvEv129S2SvPasC57BL6SwissWebsterEn1tm1GldEn1tm1GldEn2tm1AljEn2tm1AljEn1tm1GldEn2tm1Alj

decreased dopaminergic neuron number_En1<tm1Gld>/En1<tm1Gld>,En2<tm1Alj>/En2<tm1Alj>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• engrailed 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95389
• engrailed 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:95390

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• En1<tm1Gld>/En1<tm1Gld>,En2<tm1Alj>/En2<tm1Alj>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• En1<tm1Gld>|En2<tm1Alj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S2/SvPas * C57BL/6 * Swiss Webster

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased dopaminergic neuron number
  http://purl.obolibrary.org/obo/MP_0011448

文献

http://purl.org/net/cito/citesAsAuthority

• Paola. Sgadò, et.al., Slow progressive degeneration of nigral dopaminergic neurons in postnatal Engrailed mutant mice., Proceedings of the National Academy of Sciences of the United States of America, 2006, 103
  http://rdf.ncbi.nlm.nih.gov/pubmed/17015829