Paola. Sgadò, et.al., Slow progressive degeneration of nigral dopaminergic neurons in postnatal Engrailed mutant mice., Proceedings of the National Academy of Sciences of the United States of America, 2006, 103

http://rdf.ncbi.nlm.nih.gov/pubmed/17015829

Paola. Sgadò, et.al., Slow progressive degeneration of nigral dopaminergic neurons in postnatal Engrailed mutant mice., Proceedings of the National Academy of Sciences of the United States of America, 2006, 103

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• hypoactivity_En1<tm1Gld>/En1<+>,En2<tm1Alj>/En2<tm1Alj>
  http://metadb.riken.jp/0001402I129SSvEv129S2SvPasC57BL6SwissWebsterEn1tm1GldEn1En2tm1AljEn2tm1AljEn1En2tm1AljEn1tm1Gld
• loss of dopaminergic neurons_En1<tm1Gld>/En1<+>,En2<tm1Alj>/En2<tm1Alj>
  http://metadb.riken.jp/0003244I129SSvEv129S2SvPasC57BL6SwissWebsterEn1tm1GldEn1En2tm1AljEn2tm1AljEn1En2tm1AljEn1tm1Gld
• decreased dopaminergic neuron number_En1<tm1Gld>/En1<tm1Gld>,En2<tm1Alj>/En2<+>
  http://metadb.riken.jp/0011448I129SSvEv129S2SvPasC57BL6SwissWebsterEn1tm1GldEn1tm1GldEn2tm1AljEn2En2En1tm1GldEn2tm1Alj
• perinatal lethality, complete penetrance_En1<tm1Gld>/En1<tm1Gld>
  http://metadb.riken.jp/0011089I129SSvEv129S2SvPasC57BL6SwissWebsterEn1tm1GldEn1tm1GldEn1tm1Gld
• decreased neurotransmitter release_En1<tm1Gld>/En1<+>,En2<tm1Alj>/En2<tm1Alj>
  http://metadb.riken.jp/0003990I129SSvEv129S2SvPasC57BL6SwissWebsterEn1tm1GldEn1En2tm1AljEn2tm1AljEn1En2tm1AljEn1tm1Gld
• abnormal behavior_En1<tm1Gld>/En1<+>,En2<tm1Alj>/En2<tm1Alj>
  http://metadb.riken.jp/0004924I129SSvEv129S2SvPasC57BL6SwissWebsterEn1tm1GldEn1En2tm1AljEn2tm1AljEn1En2tm1AljEn1tm1Gld
• decreased food intake_En1<tm1Gld>/En1<+>,En2<tm1Alj>/En2<tm1Alj>
  http://metadb.riken.jp/0011940I129SSvEv129S2SvPasC57BL6SwissWebsterEn1tm1GldEn1En2tm1AljEn2tm1AljEn1En2tm1AljEn1tm1Gld
• perinatal lethality, complete penetrance_En1<tm1Gld>/En1<tm1Gld>,En2<tm1Alj>/En2<+>
  http://metadb.riken.jp/0011089I129SSvEv129S2SvPasC57BL6SwissWebsterEn1tm1GldEn1tm1GldEn2tm1AljEn2En2En1tm1GldEn2tm1Alj
• decreased dopaminergic neuron number_En1<tm1Gld>/En1<tm1Gld>,En2<tm1Alj>/En2<tm1Alj>
  http://metadb.riken.jp/0011448I129SSvEv129S2SvPasC57BL6SwissWebsterEn1tm1GldEn1tm1GldEn2tm1AljEn2tm1AljEn1tm1GldEn2tm1Alj
• perinatal lethality, complete penetrance_En1<tm1Gld>/En1<tm1Gld>,En2<tm1Alj>/En2<tm1Alj>
  http://metadb.riken.jp/0011089I129SSvEv129S2SvPasC57BL6SwissWebsterEn1tm1GldEn1tm1GldEn2tm1AljEn2tm1AljEn1tm1GldEn2tm1Alj
• decreased dopamine level_En1<tm1Gld>/En1<+>,En2<tm1Alj>/En2<tm1Alj>
  http://metadb.riken.jp/0005643I129SSvEv129S2SvPasC57BL6SwissWebsterEn1tm1GldEn1En2tm1AljEn2tm1AljEn1En2tm1AljEn1tm1Gld
• decreased grip strength_En1<tm1Gld>/En1<+>,En2<tm1Alj>/En2<tm1Alj>
  http://metadb.riken.jp/0010053I129SSvEv129S2SvPasC57BL6SwissWebsterEn1tm1GldEn1En2tm1AljEn2tm1AljEn1En2tm1AljEn1tm1Gld
• decreased dopaminergic neuron number_En1<tm1Gld>/En1<tm1Gld>
  http://metadb.riken.jp/0011448I129SSvEv129S2SvPasC57BL6SwissWebsterEn1tm1GldEn1tm1GldEn1tm1Gld
• slow postnatal weight gain_En1<tm1Gld>/En1<+>,En2<tm1Alj>/En2<tm1Alj>
  http://metadb.riken.jp/0008489I129SSvEv129S2SvPasC57BL6SwissWebsterEn1tm1GldEn1En2tm1AljEn2tm1AljEn1En2tm1AljEn1tm1Gld