decreased dopaminergic neuron number_Tg(Prnp-ATXN3)CVcg/Tg(Prnp-ATXN3)CVcg

http://metadb.riken.jp/0011448IC3HHeJC57BL6TgPrnpATXN3CVcgTgPrnpATXN3CVcgTgPrnpATXN3CVcg

decreased dopaminergic neuron number_Tg(Prnp-ATXN3)CVcg/Tg(Prnp-ATXN3)CVcg

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion C, Veronica Colomer Gould
  http://metadb.riken.jp/db/mgi_rdf/MGI:3798048

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Prnp-ATXN3)CVcg/Tg(Prnp-ATXN3)CVcg

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Prnp-ATXN3)CVcg

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C3H/HeJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased dopaminergic neuron number
  http://purl.obolibrary.org/obo/MP_0011448

文献

http://purl.org/net/cito/citesAsAuthority

• Daniel. Goti, et.al., A mutant ataxin-3 putative-cleavage fragment in brains of Machado-Joseph disease patients and transgenic mice is cytotoxic above a critical concentration., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/15537899