increased fibroblast proliferation_Cdkn1a<tm1Led>/Cdkn1a<tm1Led>,Gadd45a<tm1Ajf>/Gadd45a<tm1Ajf>

http://metadb.riken.jp/0011703EI129P2OlaHsd129S6SvEvTacC57BL6orI129S6SvEvTac129X1SvJC57BL6Cdkn1atm1LedCdkn1atm1LedGadd45atm1AjfGadd45atm1AjfCdkn1atm1LedGadd45atm1Ajf

increased fibroblast proliferation_Cdkn1a<tm1Led>/Cdkn1a<tm1Led>,Gadd45a<tm1Ajf>/Gadd45a<tm1Ajf>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 1A (P21)
  http://metadb.riken.jp/db/mgi_rdf/MGI:104556
• growth arrest and DNA-damage-inducible 45 alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:107799

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn1a<tm1Led>/Cdkn1a<tm1Led>,Gadd45a<tm1Ajf>/Gadd45a<tm1Ajf>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn1a<tm1Led>|Gadd45a<tm1Ajf>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: (involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased fibroblast proliferation
  http://purl.obolibrary.org/obo/MP_0011703

文献

http://purl.org/net/cito/citesAsAuthority

• M C. Hollander, et.al., Genomic instability in Gadd45a-deficient mice., Nature genetics, 1999, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/10508513