decreased pancreatic beta cell proliferation_Rictor<tm1.1Mgn>/Rictor<tm1.1Mgn>,Tg(Ins2-cre)25Mgn/0

http://metadb.riken.jp/0011820I129S6SvEvTacBALBcC57BL6DBARictortm11MgnRictortm11MgnTgIns2cre25Mgn0TgIns2cre25MgnRictortm11Mgn

decreased pancreatic beta cell proliferation_Rictor<tm1.1Mgn>/Rictor<tm1.1Mgn>,Tg(Ins2-cre)25Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• RPTOR independent companion of MTOR, complex 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926007
• transgene insertion 25, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176225

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rictor<tm1.1Mgn>/Rictor<tm1.1Mgn>,Tg(Ins2-cre)25Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Ins2-cre)25Mgn|Rictor<tm1.1Mgn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * BALB/c * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased pancreatic beta cell proliferation
  http://purl.obolibrary.org/obo/MP_0011820

文献

http://purl.org/net/cito/citesAsAuthority

• Yanyun. Gu, et.al., Rictor/mTORC2 is essential for maintaining a balance between beta-cell proliferation and cell size., Diabetes, 2011, 60
  http://rdf.ncbi.nlm.nih.gov/pubmed/21266327