decreased pancreatic beta cell proliferation_Tg(Ins2-TCF1*P291)2Kya/0

http://metadb.riken.jp/0011820IC57BL6SJLTgIns2TCF1P2912Kya0TgIns2TCF1P2912Kya

decreased pancreatic beta cell proliferation_Tg(Ins2-TCF1*P291)2Kya/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2, Kazuya Yamagata
  http://metadb.riken.jp/db/mgi_rdf/MGI:3603404

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Ins2-TCF1*P291)2Kya/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Ins2-TCF1*P291)2Kya

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased pancreatic beta cell proliferation
  http://purl.obolibrary.org/obo/MP_0011820

文献

http://purl.org/net/cito/citesAsAuthority

• Kazuya. Yamagata, et.al., Overexpression of dominant-negative mutant hepatocyte nuclear fctor-1 alpha in pancreatic beta-cells causes abnormal islet architecture with decreased expression of E-cadherin, reduced beta-cell proliferation, and diabetes., Diabetes, 2002, 51
  http://rdf.ncbi.nlm.nih.gov/pubmed/11756330