increased lymphoma incidence_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Rnf2<tm1Mvi>/Rnf2<tm1Mvi>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0012431I129C57BL6C57BL10CBASJLCdkn2atm1RdpCdkn2atm1RdpRnf2tm1MviRnf2tm1MviTgMx1cre1Cgn0Cdkn2atm1RdpTgMx1cre1CgnRnf2tm1Mvi

increased lymphoma incidence_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Rnf2<tm1Mvi>/Rnf2<tm1Mvi>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ring finger protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1101759
• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Rnf2<tm1Mvi>/Rnf2<tm1Mvi>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn2a<tm1Rdp>|Tg(Mx1-cre)1Cgn|Rnf2<tm1Mvi>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * C57BL/10 * CBA * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased lymphoma incidence
  http://purl.obolibrary.org/obo/MP_0012431

文献

http://purl.org/net/cito/citesAsAuthority

• Carmela. Calés, et.al., Inactivation of the polycomb group protein Ring1B unveils an antiproliferative role in hematopoietic cell expansion and cooperation with tumorigenesis associated with Ink4a deletion., Molecular and cellular biology, 2008, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/18039844