Carmela. Calés, et.al., Inactivation of the polycomb group protein Ring1B unveils an antiproliferative role in hematopoietic cell expansion and cooperation with tumorigenesis associated with Ink4a deletion., Molecular and cellular biology, 2008, 28

http://rdf.ncbi.nlm.nih.gov/pubmed/18039844

Carmela. Calés, et.al., Inactivation of the polycomb group protein Ring1B unveils an antiproliferative role in hematopoietic cell expansion and cooperation with tumorigenesis associated with Ink4a deletion., Molecular and cellular biology, 2008, 28

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Rnf2<tm1Mvi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3772186

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal B cell differentiation_Rnf2<tm1Mvi>/Rnf2<tm1Mvi>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002144I129S1Sv129X1SvJC57BL6C57BL10CBARnf2tm1MviRnf2tm1MviTgMx1cre1Cgn0Rnf2tm1MviTgMx1cre1Cgn
• abnormal common myeloid progenitor cell morphology_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Rnf2<tm1Mvi>/Rnf2<tm1Mvi>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0006410I129C57BL6C57BL10CBASJLCdkn2atm1RdpCdkn2atm1RdpRnf2tm1MviRnf2tm1MviTgMx1cre1Cgn0Cdkn2atm1RdpTgMx1cre1CgnRnf2tm1Mvi
• increased lymphoma incidence_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Rnf2<tm1Mvi>/Rnf2<tm1Mvi>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0012431I129C57BL6C57BL10CBASJLCdkn2atm1RdpCdkn2atm1RdpRnf2tm1MviRnf2tm1MviTgMx1cre1Cgn0Cdkn2atm1RdpTgMx1cre1CgnRnf2tm1Mvi
• enlarged liver_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Rnf2<tm1Mvi>/Rnf2<tm1Mvi>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000599I129C57BL6C57BL10CBASJLCdkn2atm1RdpCdkn2atm1RdpRnf2tm1MviRnf2tm1MviTgMx1cre1Cgn0Cdkn2atm1RdpTgMx1cre1CgnRnf2tm1Mvi
• abnormal bone marrow cell morphology/development_Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>,Rnf2<tm1Mvi>/Rnf2<tm1Mvi>
  http://metadb.riken.jp/0002398I129S1Sv129X1SvJC57BL6C57BL10SJLPolr2atm1creERT2BbdPolr2aRnf2tm1MviRnf2tm1MviPolr2atm1creERT2BbdRnf2tm1MviPolr2a
• abnormal common myeloid progenitor cell morphology_Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>,Rnf2<tm1Mvi>/Rnf2<tm1Mvi>
  http://metadb.riken.jp/0006410I129S1Sv129X1SvJC57BL6C57BL10SJLPolr2atm1creERT2BbdPolr2aRnf2tm1MviRnf2tm1MviPolr2atm1creERT2BbdRnf2tm1MviPolr2a
• decreased erythrocyte cell number_Rnf2<tm1Mvi>/Rnf2<tm1Mvi>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002875I129S1Sv129X1SvJC57BL6C57BL10CBARnf2tm1MviRnf2tm1MviTgMx1cre1Cgn0Rnf2tm1MviTgMx1cre1Cgn
• decreased bone marrow cell number_Rnf2<tm1Mvi>/Rnf2<tm1Mvi>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000333I129S1Sv129X1SvJC57BL6C57BL10CBARnf2tm1MviRnf2tm1MviTgMx1cre1Cgn0Rnf2tm1MviTgMx1cre1Cgn
• enlarged spleen_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Rnf2<tm1Mvi>/Rnf2<tm1Mvi>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000691I129C57BL6C57BL10CBASJLCdkn2atm1RdpCdkn2atm1RdpRnf2tm1MviRnf2tm1MviTgMx1cre1Cgn0Cdkn2atm1RdpTgMx1cre1CgnRnf2tm1Mvi
• decreased B cell number_Rnf2<tm1Mvi>/Rnf2<tm1Mvi>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0005017I129S1Sv129X1SvJC57BL6C57BL10CBARnf2tm1MviRnf2tm1MviTgMx1cre1Cgn0Rnf2tm1MviTgMx1cre1Cgn
• abnormal bone marrow cell morphology/development_Rnf2<tm1Mvi>/Rnf2<tm1Mvi>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002398I129S1Sv129X1SvJC57BL6C57BL10CBARnf2tm1MviRnf2tm1MviTgMx1cre1Cgn0Rnf2tm1MviTgMx1cre1Cgn
• decreased B cell number_Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>,Rnf2<tm1Mvi>/Rnf2<tm1Mvi>
  http://metadb.riken.jp/0005017I129S1Sv129X1SvJC57BL6C57BL10SJLPolr2atm1creERT2BbdPolr2aRnf2tm1MviRnf2tm1MviPolr2atm1creERT2BbdRnf2tm1MviPolr2a
• thrombocytosis_Rnf2<tm1Mvi>/Rnf2<tm1Mvi>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0005505I129S1Sv129X1SvJC57BL6C57BL10CBARnf2tm1MviRnf2tm1MviTgMx1cre1Cgn0Rnf2tm1MviTgMx1cre1Cgn
• abnormal common myeloid progenitor cell morphology_Rnf2<tm1Mvi>/Rnf2<tm1Mvi>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0006410I129S1Sv129X1SvJC57BL6C57BL10CBARnf2tm1MviRnf2tm1MviTgMx1cre1Cgn0Rnf2tm1MviTgMx1cre1Cgn
• decreased monocyte cell number_Rnf2<tm1Mvi>/Rnf2<tm1Mvi>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000223I129S1Sv129X1SvJC57BL6C57BL10CBARnf2tm1MviRnf2tm1MviTgMx1cre1Cgn0Rnf2tm1MviTgMx1cre1Cgn
• premature death_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Rnf2<tm1Mvi>/Rnf2<tm1Mvi>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002083I129C57BL6C57BL10CBASJLCdkn2atm1RdpCdkn2atm1RdpRnf2tm1MviRnf2tm1MviTgMx1cre1Cgn0Cdkn2atm1RdpTgMx1cre1CgnRnf2tm1Mvi

class

http://purl.org/net/cito/citesAsAuthority

• Rnf2<tm1Mvi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3772186