increased lymphoma incidence_Trp53<tm1Thst>/Trp53<+>,Tg(IghMyc)22Bri/0

http://metadb.riken.jp/0012431I129S1Sv129X1SvJC57BLSJLTrp53tm1ThstTrp53TgIghMyc22Bri0TgIghMyc22BriTrp53Trp53tm1Thst

increased lymphoma incidence_Trp53<tm1Thst>/Trp53<+>,Tg(IghMyc)22Bri/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 22, Ralph L Brinster
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448238
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Thst>/Trp53<+>,Tg(IghMyc)22Bri/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(IghMyc)22Bri|Trp53<+>|Trp53<tm1Thst>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased lymphoma incidence
  http://purl.obolibrary.org/obo/MP_0012431

文献

http://purl.org/net/cito/citesAsAuthority

• Oleg. Timofeev, et.al., p53 DNA binding cooperativity is essential for apoptosis and tumor suppression in vivo., Cell reports, 2013, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/23665223