increased lymphoma incidence_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Nf1<tm1Tyj>/Nf1<+>

http://metadb.riken.jp/0012431I129S2SvPas129S6SvEvTacCdkn2atm21RdpCdkn2atm21RdpNf1tm1TyjNf1Cdkn2atm21RdpNf1tm1TyjNf1

increased lymphoma incidence_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Nf1<tm1Tyj>/Nf1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• neurofibromin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97306
• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Nf1<tm1Tyj>/Nf1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn2a<tm2.1Rdp>|Nf1<tm1Tyj>|Nf1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S6/SvEvTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased lymphoma incidence
  http://purl.obolibrary.org/obo/MP_0012431

文献

http://purl.org/net/cito/citesAsAuthority

• Nancy M. Joseph, et.al., The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells., Cancer cell, 2008, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/18242513