increased embryonic neuroepithelium apoptosis_Sphk1<tm1Rlp>/Sphk1<tm1Rlp>,Sphk2<tm1Rlp>/Sphk2<tm1Rlp>

http://metadb.riken.jp/0012701I129S6SvEvTacC57BL6Sphk1tm1RlpSphk1tm1RlpSphk2tm1RlpSphk2tm1RlpSphk2tm1RlpSphk1tm1Rlp

increased embryonic neuroepithelium apoptosis_Sphk1<tm1Rlp>/Sphk1<tm1Rlp>,Sphk2<tm1Rlp>/Sphk2<tm1Rlp>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• sphingosine kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1861380
• sphingosine kinase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1316649

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sphk1<tm1Rlp>/Sphk1<tm1Rlp>,Sphk2<tm1Rlp>/Sphk2<tm1Rlp>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sphk2<tm1Rlp>|Sphk1<tm1Rlp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased embryonic neuroepithelium apoptosis
  http://purl.obolibrary.org/obo/MP_0012701

文献

http://purl.org/net/cito/citesAsAuthority

• Kiyomi. Mizugishi, et.al., Essential role for sphingosine kinases in neural and vascular development., Molecular and cellular biology, 2005, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/16314531