pancreatic acinar-to-ductal metaplasia_Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0

http://metadb.riken.jp/0013221I129S4SvJaeC57BL6CBAKrastm4TyjKrasTgPdx1cre891Dam0TgPdx1cre891DamKrastm4TyjKras

pancreatic acinar-to-ductal metaplasia_Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 89.1, Douglas A Melton
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684318
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Pdx1-cre)89.1Dam|Kras<tm4Tyj>|Kras<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• pancreatic acinar-to-ductal metaplasia
  http://purl.obolibrary.org/obo/MP_0013221

文献

http://purl.org/net/cito/citesAsAuthority

• Reginald. Hill, et.al., PTEN loss accelerates KrasG12D-induced pancreatic cancer development., Cancer research, 2010, 70
  http://rdf.ncbi.nlm.nih.gov/pubmed/20807812