decreased Paneth cell number_Xbp1<tm3Glm>/Xbp1<tm3Glm>,Tg(Vil-cre/ERT2)23Syr/0

http://metadb.riken.jp/0013486I129S6SvEvTacC57BL6DBA2Xbp1tm3GlmXbp1tm3GlmTgVilcreERT223Syr0TgVilcreERT223SyrXbp1tm3Glm

decreased Paneth cell number_Xbp1<tm3Glm>/Xbp1<tm3Glm>,Tg(Vil-cre/ERT2)23Syr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• X-box binding protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:98970
• transgene insertion 23, Sylvie Robine
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053810

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Xbp1<tm3Glm>/Xbp1<tm3Glm>,Tg(Vil-cre/ERT2)23Syr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Vil-cre/ERT2)23Syr|Xbp1<tm3Glm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased Paneth cell number
  http://purl.obolibrary.org/obo/MP_0013486

文献

http://purl.org/net/cito/citesAsAuthority

• Arthur. Kaser, et.al., XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease., Cell, 2008, 134
  http://rdf.ncbi.nlm.nih.gov/pubmed/18775308