Arthur. Kaser, et.al., XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease., Cell, 2008, 134

http://rdf.ncbi.nlm.nih.gov/pubmed/18775308

Arthur. Kaser, et.al., XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease., Cell, 2008, 134

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• small intestinal inflammation_Xbp1<tm2Glm>/Xbp1<+>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0003306I129S6SvEvTacC57BL6JFVBNSJLXbp1tm2GlmXbp1TgVil1cre997Gum0TgVil1cre997GumXbp1Xbp1tm2Glm
• increased susceptibility to bacterial infection_Xbp1<tm2Glm>/Xbp1<tm2Glm>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0002412I129S6SvEvTacC57BL6JFVBNSJLXbp1tm2GlmXbp1tm2GlmTgVil1cre997Gum0Xbp1tm2GlmTgVil1cre997Gum
• intestinal ulcer_Xbp1<tm2Glm>/Xbp1<tm2Glm>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0000512I129S6SvEvTacC57BL6JFVBNSJLXbp1tm2GlmXbp1tm2GlmTgVil1cre997Gum0Xbp1tm2GlmTgVil1cre997Gum
• cachexia_Xbp1<tm2Glm>/Xbp1<tm2Glm>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0005150I129S6SvEvTacC57BL6JFVBNSJLXbp1tm2GlmXbp1tm2GlmTgVil1cre997Gum0Xbp1tm2GlmTgVil1cre997Gum
• abnormal cell migration_Xbp1<tm2Glm>/Xbp1<tm2Glm>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0003091I129S6SvEvTacC57BL6JFVBNSJLXbp1tm2GlmXbp1tm2GlmTgVil1cre997Gum0Xbp1tm2GlmTgVil1cre997Gum
• abnormal small intestine goblet cell morphology_Xbp1<tm2Glm>/Xbp1<tm2Glm>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0013792I129S6SvEvTacC57BL6JFVBNSJLXbp1tm2GlmXbp1tm2GlmTgVil1cre997Gum0Xbp1tm2GlmTgVil1cre997Gum
• crypts of Lieberkuhn abscesses_Xbp1<tm2Glm>/Xbp1<tm2Glm>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0000491I129S6SvEvTacC57BL6JFVBNSJLXbp1tm2GlmXbp1tm2GlmTgVil1cre997Gum0Xbp1tm2GlmTgVil1cre997Gum
• abnormal intestine physiology_Xbp1<tm2Glm>/Xbp1<tm2Glm>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0010155I129S6SvEvTacC57BL6JFVBNSJLXbp1tm2GlmXbp1tm2GlmTgVil1cre997Gum0Xbp1tm2GlmTgVil1cre997Gum
• abnormal intestine physiology_Xbp1<tm3Glm>/Xbp1<tm3Glm>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0010155I129S6SvEvTacC57BL6DBA2Xbp1tm3GlmXbp1tm3GlmTgVilcreERT223Syr0TgVilcreERT223SyrXbp1tm3Glm
• decreased small intestinal villus size_Xbp1<tm3Glm>/Xbp1<tm3Glm>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0008142I129S6SvEvTacC57BL6DBA2Xbp1tm3GlmXbp1tm3GlmTgVilcreERT223Syr0TgVilcreERT223SyrXbp1tm3Glm
• abnormal endoplasmic reticulum morphology_Xbp1<tm2Glm>/Xbp1<tm2Glm>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0009378I129S6SvEvTacC57BL6JFVBNSJLXbp1tm2GlmXbp1tm2GlmTgVil1cre997Gum0Xbp1tm2GlmTgVil1cre997Gum
• decreased Paneth cell number_Xbp1<tm3Glm>/Xbp1<tm3Glm>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0013486I129S6SvEvTacC57BL6DBA2Xbp1tm3GlmXbp1tm3GlmTgVilcreERT223Syr0TgVilcreERT223SyrXbp1tm3Glm
• small intestinal inflammation_Xbp1<tm3Glm>/Xbp1<tm3Glm>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0003306I129S6SvEvTacC57BL6DBA2Xbp1tm3GlmXbp1tm3GlmTgVilcreERT223Syr0TgVilcreERT223SyrXbp1tm3Glm
• rectal hemorrhage_Xbp1<tm2Glm>/Xbp1<tm2Glm>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0003293I129S6SvEvTacC57BL6JFVBNSJLXbp1tm2GlmXbp1tm2GlmTgVil1cre997Gum0Xbp1tm2GlmTgVil1cre997Gum
• small intestinal inflammation_Xbp1<tm2Glm>/Xbp1<tm2Glm>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0003306I129S6SvEvTacC57BL6JFVBNSJLXbp1tm2GlmXbp1tm2GlmTgVil1cre997Gum0Xbp1tm2GlmTgVil1cre997Gum
• increased susceptibility to induced colitis_Xbp1<tm2Glm>/Xbp1<tm2Glm>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0008537I129S6SvEvTacC57BL6JFVBNSJLXbp1tm2GlmXbp1tm2GlmTgVil1cre997Gum0Xbp1tm2GlmTgVil1cre997Gum
• absent Paneth cells_Xbp1<tm2Glm>/Xbp1<tm2Glm>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0014076I129S6SvEvTacC57BL6JFVBNSJLXbp1tm2GlmXbp1tm2GlmTgVil1cre997Gum0Xbp1tm2GlmTgVil1cre997Gum
• increased apoptosis_Xbp1<tm3Glm>/Xbp1<tm3Glm>,Tg(Vil-cre/ERT2)23Syr/0
  http://metadb.riken.jp/0006042I129S6SvEvTacC57BL6DBA2Xbp1tm3GlmXbp1tm3GlmTgVilcreERT223Syr0TgVilcreERT223SyrXbp1tm3Glm